Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR4 | O00206 | 2/20 | 0.42 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | MMP2 | P08253 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11181948 | 0.92 | TLR4 (0.47) | TLR4ESR2MAPTMMP2 | |
| SCHEMBL5201714 | 0.86 | TLR4 (0.55) | TLR4ESR2MAPTMMP2 | |
| SCHEMBL10975419 | 0.81 | — | — | |
| SCHEMBL1867176 | 0.79 | — | — | |
| SCHEMBL9609547 | 0.78 | TLR4 (0.50) | TLR4MAPT | |
| SCHEMBL1021749 | 0.77 | TLR4 (0.53) | TLR4ESR2MAPTMMP2 | |
| SCHEMBL20725012 | 0.76 | TLR4 (0.34) | TLR4 | |
| SCHEMBL20394577 | 0.76 | MAPT (0.45) | TLR4ESR2MAPT | |
| SCHEMBL1022576 | 0.75 | TLR4 (0.52) | TLR4ESR2MAPT | |
| SCHEMBL14112201 | 0.74 | TLR4 (0.40) | TLR4ESR2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8580231-B2 | Compositions and methods comprising magnetic resonance contrast agents | NORTHWESTERN UNIVERSITY (US) | 2013-11-12 | — | — | US | disclosed |