Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 14/20 | 0.67 |
| ▸ | TACR3 | P29371 | 2/20 | 0.67 |
| ▸ | FPR1 | P21462 | 6/20 | 0.59 |
| ▸ | FPR2 | P25090 | 4/20 | 0.59 |
| ▸ | TACR2 | P21452 | 13/20 | 0.58 |
| ▸ | TAC3 | Q9UHF0 | 6/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15397605 | 1.00 | TACR1 (0.67) | TACR1TACR3FPR1FPR2TACR2 | |
| SCHEMBL13801644 | 0.87 | TACR1 (0.65) | TACR1TACR3TACR2TAC3 | |
| SCHEMBL4153912 | 0.87 | TACR1 (0.65) | TACR1TACR3TACR2TAC3 | |
| SCHEMBL4153915 | 0.87 | TACR1 (0.65) | TACR1TACR3TACR2TAC3 | |
| SCHEMBL12517759 | 0.83 | TACR1 (0.59) | TACR1TACR3TACR2TAC3 | |
| SCHEMBL13814682 | 0.81 | TACR1 (0.67) | TACR1TACR3TACR2TAC3 | |
| SCHEMBL4158529 | 0.81 | TACR1 (0.67) | TACR1TACR3TACR2TAC3 | |
| SCHEMBL13801638 | 0.81 | TACR1 (0.67) | TACR1TACR3TACR2TAC3 | |
| SCHEMBL4158533 | 0.81 | TACR1 (0.67) | TACR1TACR3TACR2TAC3 | |
| SCHEMBL4144164 | 0.81 | TACR1 (0.67) | TACR1TACR3TACR2TAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE49686-E1 | Nitrogen-containing heterocyclic compound and use of same | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2023-10-10 | — | — | US | disclosed |
| US-RE48334-E1 | Nitrogen-containing heterocyclic compound and use of same | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2020-12-01 | — | — | US | disclosed |
| US-8592454-B2 | Nitrogen-containing heterocyclic compound and use of same | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2013-11-26 | — | — | US | disclosed |