Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK13 | O15264 | 5/20 | 0.61 |
| ▸ | MAPK12 | P53778 | 5/20 | 0.61 |
| ▸ | MAPK11 | Q15759 | 5/20 | 0.61 |
| ▸ | MAPK14 | Q16539 | 5/20 | 0.61 |
| ▸ | TP53 | P04637 | 5/20 | 0.61 |
| ▸ | MAPT | P10636 | 5/20 | 0.61 |
| ▸ | GCGR | P47871 | 3/20 | 0.61 |
| ▸ | MGAM | O43451 | 1/20 | 0.59 |
| ▸ | POLB | P06746 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.52 |
| ▸ | NOX1 | Q9Y5S8 | 2/20 | 0.52 |
| ▸ | SMPD3 | Q9NY59 | 1/20 | 0.52 |
| ▸ | RAF1 | P04049 | 2/20 | 0.51 |
| ▸ | BRAF | P15056 | 1/20 | 0.51 |
| ▸ | THRB | P10828 | 1/20 | 0.50 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.48 |
| ▸ | NT5E | P21589 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8030085 | 0.83 | NOX1 (0.64) | MAPK13MAPK12MAPK11MAPK14TP53 | |
| SCHEMBL31429653 | 0.82 | MGAM (0.69) | MAPK13MAPK12MAPK11MAPK14TP53 | |
| SCHEMBL4293823 | 0.79 | MGAM (0.79) | MAPK13MAPK12MAPK11MAPK14TP53 | |
| SCHEMBL30097907 | 0.78 | MAPK13 (0.68) | MAPK13MAPK12MAPK11MAPK14TP53 | |
| SCHEMBL22408459 | 0.78 | MAPK13 (0.68) | MAPK13MAPK12MAPK11MAPK14TP53 | |
| SCHEMBL14045556 | 0.77 | MGAM (0.75) | MAPK13MAPK12MAPK11MAPK14TP53 | |
| SCHEMBL12561692 | 0.76 | MAPK13 (1.00) | MAPK13MAPK12MAPK11MAPK14TP53 | |
| SCHEMBL31559160 | 0.76 | MGAM (0.73) | MAPK13MAPK12MAPK11MAPK14TP53 | |
| SCHEMBL17133348 | 0.76 | MGAM (0.77) | MAPK13MAPK12MAPK11MAPK14TP53 | |
| SCHEMBL13379393 | 0.76 | MGAM (0.72) | MAPK13MAPK12MAPK11MAPK14TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140004071-A1 | Thermochromic Dental Material | BROWN WILLIAM STEVEN (US) | 2014-01-02 | — | — | US | disclosed |