Sugi Predict

Sugi Predict / Compounds / SCHEMBL15415401

SCHEMBL15415401

SCHEMBL15415401

O=C(O)CCC(=O)N(CCN1C(=O)C=CC1=O)CCN1C(=O)C=CC1=O

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ PTGS1 P23219 7/20 0.54
▸ PTGS2 P35354 7/20 0.54
▸ MGLL Q99685 7/20 0.41
▸ FAAH O00519 4/20 0.41
▸ ALDH1A1 P00352 2/20 0.39
▸ PKM P14618 2/20 0.39
▸ HSP90AA1 P07900 1/20 0.39
▸ TLR9 Q9NR96 1/20 0.39
▸ LMNA P02545 1/20 0.39
▸ TP53 P04637 1/20 0.39
▸ MAPT P10636 1/20 0.39
▸ HPGD P15428 1/20 0.39
▸ XBP1 P17861 1/20 0.39
▸ MAPK1 P28482 1/20 0.39
▸ HTT P42858 1/20 0.39
▸ RECQL P46063 1/20 0.39
▸ RAB9A P51151 1/20 0.39
▸ SMN1; SMN2 Q16637 1/20 0.39
▸ NPSR1 Q6W5P4 1/20 0.39
▸ GPR35 Q9HC97 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25062458 0.92 PTGS1 (0.59) PTGS1PTGS2MGLLFAAHALDH1A1
SCHEMBL21766259 0.89 PTGS1 (0.44) PTGS1PTGS2MGLLFAAHALDH1A1
SCHEMBL20763736 0.87 PTGS1 (0.43) PTGS1PTGS2MGLLFAAHALDH1A1
SCHEMBL25130211 0.86 PTGS1 (0.42) PTGS1PTGS2MGLLFAAHALDH1A1
SCHEMBL18666813 0.85 PTGS1 (0.41) PTGS1PTGS2MGLLFAAHMAPK1
SCHEMBL23286114 0.85 PTGS1 (0.41) PTGS1PTGS2MGLLFAAHALDH1A1
SCHEMBL24333477 0.83 PTGS1 (0.40) PTGS1PTGS2MGLLFAAHALDH1A1
SCHEMBL19915463 0.83 PTGS1 (0.40) PTGS1PTGS2
SCHEMBL14103629 0.81 PTGS1 (0.41) PTGS1PTGS2MGLLFAAHALDH1A1
SCHEMBL26421390 0.81 PTGS1 (0.38) PTGS1PTGS2MGLLFAAHALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 66 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025021118-A9 LIGAND-DRUG CONJUGATE AND LINKER FOR CONJUGATION 海南先声再明医药股份有限公司 2025-04-03 — — WO disclosed
WO-2025021118-A1 LIGAND-DRUG CONJUGATE AND LINKER FOR CONJUGATION 海南先声再明医药股份有限公司 2025-01-30 — — WO disclosed
EP-4426727-A2 SPECIFIC CONJUGATION OF AN ANTIBODY Hangzhou Dac Biotech Co., Ltd. (CN) 2024-09-11 — — EP disclosed
CN-117801107-A Benzazepine derivatives, conjugates containing same and application thereof 上海迪诺医药科技有限公司 2024-04-02 — — CN disclosed
US-11834406-B2 Conjugates of cell binding molecules with cytotoxic agents HANGZHOU DAC BIOTECH CO., LTD. (CN) 2023-12-05 — — US disclosed
US-11834406-B2 Conjugates of cell binding molecules with cytotoxic agents HANGZHOU DAC BIOTECH CO., LTD. (CN) 2023-12-05 — — US disclosed
US-11834406-B2 Conjugates of cell binding molecules with cytotoxic agents HANGZHOU DAC BIOTECH CO., LTD. (CN) 2023-12-05 — — US disclosed
US-11767294-B2 Conjugates of cell binding molecules with cytotoxic agents HANGZHOU DAC BIOTECH CO., LTD. (CN) 2023-09-26 — — US disclosed
US-11767294-B2 Conjugates of cell binding molecules with cytotoxic agents HANGZHOU DAC BIOTECH CO., LTD. (CN) 2023-09-26 — — US disclosed
US-11767294-B2 Conjugates of cell binding molecules with cytotoxic agents HANGZHOU DAC BIOTECH CO., LTD. (CN) 2023-09-26 — — US disclosed
US-20170157262-A1 CONJUGATES OF CELL BINDING MOLECULES WITH CYTOTOXIC AGENTS HANGZHOU DAC BIOTECH CO., LTD (CN) 2017-06-08 — — US disclosed
US-20170157262-A1 CONJUGATES OF CELL BINDING MOLECULES WITH CYTOTOXIC AGENTS HANGZHOU DAC BIOTECH CO., LTD (CN) 2017-06-08 — — US disclosed
US-20170157262-A1 CONJUGATES OF CELL BINDING MOLECULES WITH CYTOTOXIC AGENTS HANGZHOU DAC BIOTECH CO., LTD (CN) 2017-06-08 — — US disclosed
WO-2017046658-A1 DERIVATIVES OF AMANITA TOXINS AND THEIR CONJUGATION TO A CELL BINDING MOLECULE HANGZHOU DAC BIOTECH CO, LTD (CN) 2017-03-23 — — WO disclosed
US-20160015832-A1 TRIDENTATE CONNEXON AND USE THEREOF NEWBIO THERAPEUTICS, INC. (CN) 2016-01-21 — — US disclosed
US-20160015832-A1 TRIDENTATE CONNEXON AND USE THEREOF NEWBIO THERAPEUTICS, INC. (CN) 2016-01-21 — — US disclosed
EP-2949343-A1 TRIDENTATE CONNEXON AND USE THEREOF Newbio Therapeutics Inc. (CN) 2015-12-02 — — EP disclosed
EP-2872157-A1 CONJUGATES OF CELL BINDING MOLECULES WITH CYTOTOXIC AGENTS Hangzhou Dac Biotech Co., Ltd (CN) 2015-05-20 — — EP disclosed
WO-2014009774-A1 CONJUGATES OF CELL BINDING MOLECULES WITH CYTOTOXIC AGENTS HANGZHOU DAC BIOTECH CO., LTD (CN) 2014-01-16 — — WO disclosed
WO-2014009774-A1 CONJUGATES OF CELL BINDING MOLECULES WITH CYTOTOXIC AGENTS HANGZHOU DAC BIOTECH CO., LTD (CN) 2014-01-16 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160015832-A1 TRIDENTATE CONNEXON AND USE THEREOF DNTT, CD2, CD4 PTGS1 4578/4885PTGS2 4792/4885MGLL 1086/4885
US-20170157262-A1 CONJUGATES OF CELL BINDING MOLECULES WITH CYTOTOXIC AGENTS CD4, CD2, CD47 PTGS1 4563/4885PTGS2 4820/4885MGLL 3277/4885
US-11767294-B2 Conjugates of cell binding molecules with cytotoxic agents CD4, CD2, CD47 PTGS1 4300/4885PTGS2 4827/4885MGLL 3221/4885
US-11834406-B2 Conjugates of cell binding molecules with cytotoxic agents CD4, CD2, CD47 PTGS1 4442/4885PTGS2 4810/4885MGLL 3175/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.