Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK2 | O60674 | 20/20 | 0.77 |
| ▸ | JAK3 | P52333 | 20/20 | 0.77 |
| ▸ | PTK2 | Q05397 | 20/20 | 0.77 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2634207 | 0.87 | JAK3 (1.00) | JAK2JAK3PTK2 | |
| SCHEMBL15416892 | 0.85 | JAK3 (0.81) | JAK2JAK3PTK2 | |
| SCHEMBL2634719 | 0.84 | JAK2 (1.00) | JAK2JAK3PTK2 | |
| SCHEMBL2634735 | 0.84 | JAK3 (1.00) | JAK2JAK3PTK2 | |
| SCHEMBL15416874 | 0.82 | JAK3 (0.81) | JAK2JAK3PTK2 | |
| SCHEMBL15416791 | 0.81 | JAK3 (0.82) | JAK2JAK3PTK2 | |
| SCHEMBL3213421 | 0.80 | JAK2 (0.76) | JAK2JAK3PTK2 | |
| SCHEMBL15416893 | 0.80 | JAK3 (0.81) | JAK2JAK3PTK2 | |
| SCHEMBL3760028 | 0.79 | JAK3 (0.82) | JAK2JAK3PTK2 | |
| SCHEMBL12973798 | 0.79 | JAK3 (0.85) | JAK2JAK3PTK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8633173-B2 | Preparation and uses of 1,2,4-triazolo [1,5a] pyridine derivatives | CEPHALON, INC (US) | 2014-01-21 | — | — | US | disclosed |