Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15418714 | 0.93 | BACE1 (0.64) | BACE1CTSD | |
| SCHEMBL2522209 | 0.88 | BACE1 (0.65) | BACE1CTSD | |
| SCHEMBL2522204 | 0.88 | BACE1 (0.65) | BACE1CTSD | |
| SCHEMBL2520008 | 0.87 | BACE1 (0.84) | BACE1CTSD | |
| SCHEMBL15418702 | 0.86 | BACE1 (0.61) | BACE1CTSD | |
| SCHEMBL2525687 | 0.85 | BACE1 (0.59) | BACE1CTSD | |
| SCHEMBL2526343 | 0.85 | BACE1 (0.59) | BACE1CTSD | |
| SCHEMBL12213374 | 0.84 | BACE1 (0.64) | BACE1CTSD | |
| SCHEMBL15418744 | 0.80 | BACE1 (0.65) | BACE1CTSD | |
| SCHEMBL15418860 | 0.80 | BACE1 (0.62) | BACE1CTSD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2547686-B1 | AMINO-DIHYDROOXAZINE AND AMINO-DIHYDROTHIAZINE SPIRO COMPOUNDS AS BETA-SECRETASE MODULATORS AND THEIR MEDICAL USE | AMGEN INC (US) | 2014-01-22 | — | — | EP | disclosed |