Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15418921 | 0.92 | BACE1 (0.58) | BACE1CTSD | |
| SCHEMBL2527980 | 0.92 | BACE1 (0.62) | BACE1CTSD | |
| SCHEMBL2527977 | 0.92 | BACE1 (0.62) | BACE1CTSD | |
| SCHEMBL2525830 | 0.91 | BACE1 (0.64) | BACE1CTSD | |
| SCHEMBL2523399 | 0.91 | BACE1 (0.64) | BACE1CTSD | |
| SCHEMBL15418906 | 0.89 | BACE1 (0.59) | BACE1CTSD | |
| SCHEMBL2524862 | 0.88 | BACE1 (0.60) | BACE1CTSD | |
| SCHEMBL2524867 | 0.88 | BACE1 (0.60) | BACE1CTSD | |
| SCHEMBL15418810 | 0.85 | BACE1 (0.44) | BACE1CTSD | |
| SCHEMBL2523429 | 0.85 | BACE1 (0.64) | BACE1CTSD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2547686-B1 | AMINO-DIHYDROOXAZINE AND AMINO-DIHYDROTHIAZINE SPIRO COMPOUNDS AS BETA-SECRETASE MODULATORS AND THEIR MEDICAL USE | AMGEN INC (US) | 2014-01-22 | — | — | EP | disclosed |