SCHEMBL15419005

SCHEMBL15419005

CCCCCNc1nc(N)nc(C)c1Cc1ccc(OCCOCCP(=O)(O)O)cc1OC

nearest known ligand 0.65

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
TLR7 Q9NYK1 20/20 0.65

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22870406 0.90 TLR7 (0.66) TLR7
SCHEMBL255165 0.90 TLR7 (0.58) TLR7
SCHEMBL10310955 0.89 TLR7 (0.62) TLR7
SCHEMBL15419006 0.88 TLR7 (0.61) TLR7
SCHEMBL10311334 0.88 TLR7 (0.61) TLR7
SCHEMBL853470 0.87 TLR7 (0.72) TLR7
SCHEMBL10310958 0.86 TLR7 (0.57) TLR7
SCHEMBL14471932 0.84 TLR7 (0.69) TLR7
SCHEMBL2847017 0.84 TLR7 (0.75) TLR7
SCHEMBL3701040 0.83 TLR7 (0.63) TLR7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2719395-A1 Adsorption of immunopotentiators to insoluble metal salts Novartis AG (CH) 2014-04-16 EP disclosed
EP-2480253-B1 ADSORPTION OF IMMUNOPOTENTIATORS TO INSOLUBLE METAL SALTS NOVARTIS AG (CH) 2014-01-22 EP disclosed