Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 19/20 | 0.73 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL259996 | 0.84 | PDE10A (1.00) | PDE10A | |
| SCHEMBL259090 | 0.84 | PDE10A (1.00) | PDE10A | |
| SCHEMBL260001 | 0.78 | PDE10A (1.00) | PDE10A | |
| SCHEMBL259752 | 0.77 | PDE10A (1.00) | PDE10A | |
| SCHEMBL259697 | 0.76 | PDE10A (1.00) | PDE10A | |
| SCHEMBL2044097 | 0.76 | PDE10A (1.00) | PDE10A | |
| SCHEMBL259154 | 0.75 | PDE10A (1.00) | PDE10A | |
| SCHEMBL260508 | 0.75 | PDE10A (1.00) | PDE10A | |
| SCHEMBL259747 | 0.73 | PDE10A (1.00) | PDE10A | |
| SCHEMBL260199 | 0.72 | PDE10A (1.00) | PDE10A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2318394-B1 | NOVEL PHENYLIMIDAZOLE DERIVATIVES AS PDE10A ENZYME INHIBITORS | LUNDBECK & CO AS H (DK) | 2014-01-22 | — | — | EP | claimed |