⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15425908 | 1.00 | — | — | |
| SCHEMBL15425909 | 1.00 | — | — | |
| SCHEMBL15425910 | 1.00 | — | — | |
| SCHEMBL15410658 | 0.75 | — | — | |
| SCHEMBL15410523 | 0.75 | — | — | |
| SCHEMBL24633451 | 0.75 | — | — | |
| SCHEMBL471760 | 0.75 | — | — | |
| SCHEMBL424208 | 0.75 | — | — | |
| SCHEMBL15409418 | 0.75 | — | — | |
| SCHEMBL8204702 | 0.72 | MEN1 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10010525-B2 | Methods of inducing anesthesia | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2018-07-03 | — | — | US | disclosed |
| US-20180116997-A1 | METHODS OF INDUCING ANESTHESIA | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2018-05-03 | — | — | US | disclosed |
| US-9381185-B2 | Methods of inducing sedation | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2016-07-05 | — | — | US | disclosed |
| US-20150157596-A1 | METHODS OF INDUCING SEDATION | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2015-06-11 | — | — | US | disclosed |
| US-20140018414-A1 | METHODS OF INDUCING ANESTHESIA | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2014-01-16 | — | — | US | disclosed |