SCHEMBL15426460

SCHEMBL15426460

CC[S+]([O-])c1cc(S(F)(F)(F)(F)F)ccc1-c1nc2cc(C)cnc2n1C

nearest known ligand 0.31

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
AKT1 P31749 2/20 0.31
AKT2 P31751 2/20 0.31
BRD4 O60885 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15427213 0.88 POLB (0.40)
SCHEMBL15426383 0.86 GRIN1 (0.33) AKT1AKT2BRD4
SCHEMBL15426389 0.84 TNKS (0.35) AKT1AKT2BRD4
SCHEMBL15426454 0.84 AKT1 (0.32) AKT1AKT2BRD4
SCHEMBL15426412 0.83 POLB (0.36) AKT1AKT2BRD4
SCHEMBL15412909 0.82 BRD4 (0.38) AKT1AKT2BRD4
SCHEMBL16746509 0.81 BRD4 (0.33) BRD4
SCHEMBL10249039 0.81 PDE10A (0.35) AKT1AKT2BRD4
SCHEMBL15426459 0.79 AKT1 (0.31) AKT1AKT2BRD4
SCHEMBL16803693 0.78 PDE10A (0.35) AKT1AKT2BRD4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9278983-B2 Fused heterocyclic compound and use thereof for pest control SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2016-03-08 US disclosed
US-20140364444-A1 FUSED HETEROCYCLIC COMPOUND AND USE THEREOF FOR PEST CONTROL SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2014-12-11 US disclosed
US-8853238-B2 Fused heterocyclic compound and use thereof for pest control SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2014-10-07 US disclosed
US-20140018373-A1 FUSED HETEROCYCLIC COMPOUND AND USE FOR PEST CONTROL THEREOF SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2014-01-16 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140018373-A1 FUSED HETEROCYCLIC COMPOUND AND USE FOR PEST CONTROL THEREOF NR4A1, NR2C2, NR0B1 AKT1 1919/4885AKT2 2509/4885BRD4 1677/4885
US-20140364444-A1 FUSED HETEROCYCLIC COMPOUND AND USE THEREOF FOR PEST CONTROL NR4A1, NR2C2, NR0B1 AKT1 1808/4885AKT2 2400/4885BRD4 1616/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.