⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11352404 | 0.79 | TSHR (0.46) | — | |
| SCHEMBL9402144 | 0.78 | TSHR (0.41) | — | |
| SCHEMBL854739 | 0.77 | — | — | |
| SCHEMBL13127158 | 0.75 | — | — | |
| SCHEMBL13127159 | 0.75 | — | — | |
| SCHEMBL25405538 | 0.75 | — | — | |
| SCHEMBL561443 | 0.75 | — | — | |
| SCHEMBL191784 | 0.75 | — | — | |
| SCHEMBL9402142 | 0.75 | — | — | |
| SCHEMBL13127072 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104884439-B | Produce the method and halogen hydantoin compound of halogen hydantoin compound | 日宝化学株式会社 | 2019-10-18 | — | — | CN | disclosed |
| CN-104903298-B | Process for producing halohydantoin compounds | 日宝化学株式会社 | 2018-05-15 | — | — | CN | disclosed |
| CN-104854095-B | Produce method and apparatus, method for recycling and the halogen hydantoin compound of halogen hydantoin compound | 日宝化学株式会社 | 2018-01-30 | — | — | CN | disclosed |
| EP-2870153-B1 | SULFONYL CONTAINING BENZOTHIAZOLE INHIBITORS OF ENDOTHELIAL LIPASE | BRISTOL MYERS SQUIBB CO (US) | 2016-11-02 | — | — | EP | disclosed |
| CN-104903298-A | Process for producing halohydantoin compounds | NIPPOH CHEMICALS | 2015-09-09 | — | — | CN | disclosed |
| CN-104884439-A | Production method for halohydrantoin compound and halohydrantoin compound | NIPPOH CHEMICALS | 2015-09-02 | — | — | CN | disclosed |
| CN-104854095-A | PRODUCTION METHOD AND PRODUCTION DEVICE FOR HALO-HYDANTOIN COMPOUND, REUSE SYSTEM, AND HALO-HYDANTOIN COMPOUND | NIPPOH CHEMICALS | 2015-08-19 | — | — | CN | disclosed |
| WO-2014042939-A1 | KETONE LINKED BENZOTHIAZOLE INHIBITORS OF ENDOTHELIAL LIPASE | BRISTOL-MYERS SQUIBB COMPANY (US) | 2014-03-20 | — | — | WO | disclosed |
| WO-2014011513-A1 | SULFONYL CONTAINING BENZOTHIAZOLE INHIBITORS OF ENDOTHELIAL LIPASE | BRISTOL-MYERS SQUIBB COMPANY (US) | 2014-01-16 | — | — | WO | disclosed |