Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XIAP | P98170 | 20/20 | 1.00 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17323417 | 1.00 | XIAP (1.00) | XIAP | |
| Hydrochloric Acid SCHEMBL15414152 | 0.99 | XIAP (1.00) | XIAP | |
| Hydrochloric Acid SCHEMBL15414151 | 0.99 | XIAP (1.00) | XIAP | |
| Hydrochloric Acid SCHEMBL15414153 | 0.99 | XIAP (1.00) | XIAP | |
| SCHEMBL19835086 | 0.94 | XIAP (1.00) | XIAP | |
| SCHEMBL15427493 | 0.94 | XIAP (1.00) | XIAP | |
| SCHEMBL17323418 | 0.94 | XIAP (1.00) | XIAP | |
| Hydrochloric Acid SCHEMBL15414695 | 0.93 | XIAP (0.98) | XIAP | |
| Hydrochloric Acid SCHEMBL15414697 | 0.93 | XIAP (0.98) | XIAP | |
| Hydrochloric Acid SCHEMBL15414699 | 0.93 | XIAP (0.98) | XIAP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2872490-B1 | ANTIPROLIFERATIVE BENZO[B]AZEPIN-2-ONES | HOFFMANN LA ROCHE (CH) | 2018-02-07 | — | — | EP | disclosed |
| WO-2014009495-A1 | ANTIPROLIFERATIVE BENZO [B] AZEPIN- 2 - ONES | F. HOFFMANN-LA ROCHE AG (CH) | 2014-01-16 | — | — | WO | disclosed |