Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6892879 | 0.91 | PIK3CA (1.00) | PIK3CAMTOR | |
| SCHEMBL12136262 | 0.89 | MTOR (0.72) | PIK3CAMTOR | |
| SCHEMBL6891606 | 0.88 | MTOR (1.00) | PIK3CAMTOR | |
| SCHEMBL6893647 | 0.85 | PIK3CA (1.00) | PIK3CAMTOR | |
| SCHEMBL6893093 | 0.84 | PIK3CA (1.00) | PIK3CAMTOR | |
| SCHEMBL6892508 | 0.84 | PIK3CA (1.00) | PIK3CAMTOR | |
| SCHEMBL6892048 | 0.83 | PIK3CA (0.88) | PIK3CAMTOR | |
| SCHEMBL6894693 | 0.83 | MTOR (1.00) | PIK3CAMTOR | |
| SCHEMBL6893505 | 0.83 | PIK3CA (1.00) | PIK3CAMTOR | |
| SCHEMBL6892908 | 0.83 | PIK3CA (1.00) | PIK3CAMTOR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8633183-B2 | 5-alkynyl-pyrimidines | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2014-01-21 | — | — | US | disclosed |