Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK2 | O60674 | 20/20 | 0.72 |
| ▸ | PTK2 | Q05397 | 20/20 | 0.72 |
| ▸ | JAK3 | P52333 | 14/20 | 0.72 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15428957 | 0.91 | JAK2 (0.72) | JAK2PTK2JAK3 | |
| SCHEMBL3764437 | 0.84 | JAK2 (1.00) | JAK2PTK2JAK3 | |
| SCHEMBL2634312 | 0.81 | JAK2 (1.00) | JAK2PTK2JAK3 | |
| SCHEMBL15428959 | 0.79 | JAK2 (0.74) | JAK2PTK2JAK3 | |
| SCHEMBL2640561 | 0.79 | JAK2 (0.70) | JAK2PTK2JAK3 | |
| SCHEMBL2634737 | 0.76 | JAK2 (1.00) | JAK2PTK2JAK3 | |
| SCHEMBL2640525 | 0.75 | JAK2 (1.00) | JAK2PTK2JAK3 | |
| SCHEMBL2640566 | 0.75 | JAK2 (1.00) | JAK2PTK2JAK3 | |
| SCHEMBL2634356 | 0.75 | JAK2 (1.00) | JAK2PTK2JAK3 | |
| SCHEMBL3770418 | 0.74 | JAK2 (0.74) | JAK2PTK2JAK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8633173-B2 | Preparation and uses of 1,2,4-triazolo [1,5a] pyridine derivatives | CEPHALON, INC (US) | 2014-01-21 | — | — | US | disclosed |
| US-8633173-B2 | Preparation and uses of 1,2,4-triazolo [1,5a] pyridine derivatives | CEPHALON, INC (US) | 2014-01-21 | — | — | US | disclosed |