Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | RARB | P10826 | 3/20 | 0.41 |
| ▸ | RARA | P10276 | 1/20 | 0.41 |
| ▸ | RARG | P13631 | 1/20 | 0.41 |
| ▸ | ESR1 | P03372 | 2/20 | 0.41 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.41 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.41 |
| ▸ | TACR2 | P21452 | 2/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | SHBG | P04278 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.41 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12611127 | 1.00 | HSD17B10 (0.42) | HSD17B10TSHRRARBRARARARG | |
| SCHEMBL8978727 | 0.91 | HSD17B10 (0.47) | HSD17B10TSHRRARBRARARARG | |
| SCHEMBL8978945 | 0.91 | HSD17B10 (0.47) | HSD17B10TSHRRARBRARARARG | |
| SCHEMBL8979053 | 0.91 | HSD17B10 (0.47) | HSD17B10TSHRRARBRARARARG | |
| SCHEMBL8978954 | 0.91 | HSD17B10 (0.47) | HSD17B10TSHRRARBRARARARG | |
| SCHEMBL8978783 | 0.91 | HSD17B10 (0.47) | HSD17B10TSHRRARBRARARARG | |
| SCHEMBL8978771 | 0.91 | HSD17B10 (0.47) | HSD17B10TSHRRARBRARARARG | |
| SCHEMBL8979075 | 0.91 | HSD17B10 (0.47) | HSD17B10TSHRRARBRARARARG | |
| SCHEMBL8978943 | 0.91 | HSD17B10 (0.47) | HSD17B10TSHRRARBRARARARG | |
| SCHEMBL8979110 | 0.91 | HSD17B10 (0.47) | HSD17B10TSHRRARBRARARARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9296948-B2 | Mesogenic compounds, liquid-crystalline media and components for high-frequency technology | MERCK PATENT GMBH (DE) | 2016-03-29 | — | — | US | disclosed |
| US-20140021405-A1 | MESOGENIC COMPOUNDS, LIQUID-CRYSTALLINE MEDIA AND COMPONENTS FOR HIGH-FREQUENCY TECHNOLOGY | MERCK PATENT GMBH (DE) | 2014-01-23 | — | — | US | disclosed |