Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 5/20 | 0.66 |
| ▸ | GAA | P10253 | 1/20 | 0.60 |
| ▸ | HPGD | P15428 | 1/20 | 0.60 |
| ▸ | HDAC1 | Q13547 | 5/20 | 0.56 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.56 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.56 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.52 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10094805 | 0.98 | TRPV1 (0.63) | TRPV1GAAHPGDHDAC1ALOX5 | |
| SCHEMBL10094798 | 0.95 | GAA (0.62) | TRPV1GAAHPGDHDAC1HDAC2 | |
| SCHEMBL60236 | 0.87 | MEN1 (0.65) | GAAHPGDMAPTALDH1A1MEN1 | |
| SCHEMBL15433150 | 0.87 | TRPV1 (0.54) | TRPV1GAAHPGDHDAC1ALOX5 | |
| Hydrochloric Acid SCHEMBL6208128 | 0.85 | MEN1 (0.63) | GAAHPGDMAPTALDH1A1MEN1 | |
| Water SCHEMBL27340800 | 0.85 | MEN1 (0.63) | GAAHPGDMAPTALDH1A1MEN1 | |
| SCHEMBL11337600 | 0.85 | MEN1 (0.63) | GAAHPGDMAPTALDH1A1MEN1 | |
| SCHEMBL5990328 | 0.84 | HDAC1 (0.72) | HPGDHDAC1ALOX5HDAC2MAPT | |
| SCHEMBL8009605 | 0.84 | HDAC1 (0.72) | HPGDHDAC1ALOX5HDAC2MAPT | |
| SCHEMBL16658763 | 0.84 | HDAC1 (0.72) | HPGDHDAC1ALOX5HDAC2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140024608-A1 | INHIBITORS OF HISTONE DEACETYLASE AND PRODRUGS THEREOF | METHYLGENE INC. (CA) | 2014-01-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140024608-A1 | INHIBITORS OF HISTONE DEACETYLASE AND PRODRUGS THEREOF | HDAC1, HDAC3, HDAC11 | TRPV1 3547/4885GAA 182/4885HPGD 348/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.