SCHEMBL15433192

SCHEMBL15433192

CCC/C(F)=C(\F)c1ccc(C2CCC(c3cc(F)c(F)c(F)c3)CC2)cc1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2C9 P11712 1/20 0.38
ALDH1A1 P00352 4/20 0.36
MAPT P10636 3/20 0.36
MEN1 O00255 2/20 0.36
KMT2A Q03164 2/20 0.36
LMNA P02545 2/20 0.36
MAPK1 P28482 1/20 0.36
HPGD P15428 3/20 0.33
SMN1; SMN2 Q16637 2/20 0.33
GAA P10253 1/20 0.33
RAB9A P51151 3/20 0.33
NPC1 O15118 2/20 0.33
NPSR1 Q6W5P4 1/20 0.33
ESRRB O95718 2/20 0.31
ESR1 P03372 2/20 0.31
ESRRG P62508 2/20 0.31
KCNH2 Q12809 2/20 0.31
USP5 P45974 1/20 0.31
HDAC6 Q9UBN7 1/20 0.31
ESR2 Q92731 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15433191 0.89 CYP2C9 (0.37) CYP2C9ALDH1A1MAPTMEN1KMT2A
SCHEMBL15433217 0.87 CYP2C9 (0.38) CYP2C9ALDH1A1MAPTMEN1KMT2A
SCHEMBL15433843 0.86 CYP2C9 (0.30) CYP2C9
SCHEMBL15433415 0.84 HPGD (0.32) ALDH1A1MAPTMEN1KMT2AHPGD
SCHEMBL15433839 0.84 SPHK1 (0.34) CYP2C9SPHK1
SCHEMBL15433689 0.82 SPHK1 (0.36) CYP2C9ALDH1A1MAPTLMNAESRRB
SCHEMBL15433190 0.81 ESR2 (0.35) CYP2C9ALDH1A1MAPTMEN1KMT2A
SCHEMBL7230477 0.81 CYP2C9 (0.59) CYP2C9ALDH1A1MAPTMEN1KMT2A
SCHEMBL15433856 0.80 OPRL1 (0.36) CYP2C9ALDH1A1MAPTMEN1KMT2A
SCHEMBL15433243 0.79 SPHK1 (0.34) CYP2C9ALDH1A1MAPTMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8956551-B2 Liquid crystal compound having fluorovinyl group, liquid crystal composition and liquid crystal display device JNC CORPORATION (JP) 2015-02-17 US disclosed
US-8956551-B2 Liquid crystal compound having fluorovinyl group, liquid crystal composition and liquid crystal display device JNC CORPORATION (JP) 2015-02-17 US disclosed
US-20140021406-A1 LIQUID CRYSTAL COMPOUND HAVING FLUOROVINYL GROUP, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE JNC PETROCHEMICAL CORPORATION (JP) 2014-01-23 US disclosed
US-20140021406-A1 LIQUID CRYSTAL COMPOUND HAVING FLUOROVINYL GROUP, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE JNC PETROCHEMICAL CORPORATION (JP) 2014-01-23 US disclosed