SCHEMBL15433561

SCHEMBL15433561

CCCC/C(F)=C(\F)c1ccc(C2CCC(CCC3CCC(c4cc(F)c(F)c(F)c4)CC3)CC2)c(F)c1

nearest known ligand 0.39

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
OPRL1 P41146 15/20 0.36
CYP2C9 P11712 1/20 0.36
ALDH1A1 P00352 1/20 0.34
LMNA P02545 1/20 0.34
MAPT P10636 1/20 0.34
MEN1 O00255 1/20 0.34
MAPK1 P28482 1/20 0.34
KMT2A Q03164 1/20 0.34
GRM2 Q14416 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15433890 0.94 OPRL1 (0.33) OPRL1CYP2C9ALDH1A1LMNAMAPT
SCHEMBL15433856 0.91 OPRL1 (0.36) OPRL1CYP2C9ALDH1A1LMNAMAPT
SCHEMBL8434276 0.86 OPRL1 (0.38) OPRL1CYP2C9ALDH1A1LMNAMAPT
SCHEMBL7240424 0.86 OPRL1 (0.38) OPRL1CYP2C9ALDH1A1LMNAMAPT
SCHEMBL15433415 0.85 HPGD (0.32) OPRL1ALDH1A1MAPTMEN1KMT2A
SCHEMBL15433839 0.84 SPHK1 (0.34) CYP2C9
SCHEMBL15433194 0.83 OPRL1 (0.33) OPRL1ALDH1A1MAPT
SCHEMBL15433419 0.82
SCHEMBL15433198 0.82
SCHEMBL15433857 0.81 CYP2C9 (0.32) OPRL1CYP2C9ALDH1A1LMNAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8956551-B2 Liquid crystal compound having fluorovinyl group, liquid crystal composition and liquid crystal display device JNC CORPORATION (JP) 2015-02-17 US disclosed
US-8956551-B2 Liquid crystal compound having fluorovinyl group, liquid crystal composition and liquid crystal display device JNC CORPORATION (JP) 2015-02-17 US disclosed
US-20140021406-A1 LIQUID CRYSTAL COMPOUND HAVING FLUOROVINYL GROUP, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE JNC PETROCHEMICAL CORPORATION (JP) 2014-01-23 US disclosed
US-20140021406-A1 LIQUID CRYSTAL COMPOUND HAVING FLUOROVINYL GROUP, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE JNC PETROCHEMICAL CORPORATION (JP) 2014-01-23 US disclosed