Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 19/20 | 0.68 |
| ▸ | SLC6A4 | P31645 | 16/20 | 0.66 |
| ▸ | SLC6A3 | Q01959 | 7/20 | 0.66 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.66 |
| ▸ | HTR2C | P28335 | 1/20 | 0.66 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.64 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12694069 | 1.00 | SLC6A2 (0.68) | SLC6A2SLC6A4SLC6A3CYP2D6HTR2C | |
| SCHEMBL14143440 | 1.00 | SLC6A2 (0.68) | SLC6A2SLC6A4SLC6A3CYP2D6HTR2C | |
| SCHEMBL3422142 | 0.88 | SLC6A2 (0.66) | SLC6A2SLC6A4SLC6A3CYP2D6HTR2C | |
| SCHEMBL12459423 | 0.88 | SLC6A2 (0.66) | SLC6A2SLC6A4SLC6A3CYP2D6HTR2C | |
| SCHEMBL15433977 | 0.86 | SLC6A2 (0.64) | SLC6A2SLC6A4SLC6A3CYP2D6HTR2C | |
| SCHEMBL5527451 | 0.86 | SLC6A2 (0.67) | SLC6A2SLC6A4SLC6A3CYP2D6HTR2C | |
| SCHEMBL6023093 | 0.84 | SLC6A2 (0.49) | SLC6A2SLC6A4SLC6A3CYP2D6HTR2C | |
| SCHEMBL13835677 | 0.84 | SLC6A2 (0.49) | SLC6A2SLC6A4SLC6A3CYP2D6HTR2C | |
| SCHEMBL3745740 | 0.84 | SLC6A2 (0.49) | SLC6A2SLC6A4SLC6A3CYP2D6HTR2C | |
| SCHEMBL4025741 | 0.82 | SLC6A2 (0.48) | SLC6A2SLC6A4SLC6A3CYP2D6HTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014009767-A1 | AN IMPROVED PROCESS FOR THE PREPARATION OF 1-ARYL 2-AMINOMETHYL CYCLOPROPANE CARBOXYAMIDE (Z) DERIVATIVES, THEIR ISOMERS AND SALTS | MICRO LABS LIMITED (IN) | 2014-01-16 | — | — | WO | disclosed |