Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR6 | P51684 | 19/20 | 0.53 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2520646 | 1.00 | CCR6 (0.53) | CCR6CXCR2 | |
| SCHEMBL13494940 | 1.00 | CCR6 (0.53) | CCR6CXCR2 | |
| SCHEMBL12205444 | 0.92 | CCR6 (0.57) | CCR6CXCR2 | |
| SCHEMBL20452591 | 0.91 | CXCR2 (0.63) | CCR6CXCR2 | |
| SCHEMBL1579026 | 0.91 | CXCR2 (0.63) | CCR6CXCR2 | |
| SCHEMBL30515703 | 0.91 | CXCR2 (0.63) | CCR6CXCR2 | |
| SCHEMBL1705955 | 0.90 | CCR6 (0.54) | CCR6CXCR2 | |
| SCHEMBL1706337 | 0.89 | CCR6 (0.56) | CCR6CXCR2 | |
| SCHEMBL1706485 | 0.89 | CCR6 (0.64) | CCR6 | |
| SCHEMBL1706049 | 0.89 | CCR6 (0.55) | CCR6CXCR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2310359-B1 | ORGANIC COMPOUNDS | NOVARTIS AG (CH) | 2014-01-15 | — | — | EP | disclosed |