SCHEMBL15434992

SCHEMBL15434992

CON(C)S(=O)(=O)c1c(Cl)ccc(Nc2c(N[C@@H](C)c3ccc(F)cc3)c(=O)c2=O)c1O

nearest known ligand 0.60

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
CXCR2 P25025 1/20 0.60
CCR6 P51684 19/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2299062 1.00 CXCR2 (0.60) CXCR2CCR6
SCHEMBL2299061 1.00 CXCR2 (0.60) CXCR2CCR6
SCHEMBL2295954 0.92 CXCR2 (0.63) CXCR2CCR6
SCHEMBL2295957 0.92 CXCR2 (0.63) CXCR2CCR6
SCHEMBL12205569 0.92 CXCR2 (0.63) CXCR2CCR6
SCHEMBL2297372 0.91 CCR6 (0.68) CXCR2CCR6
SCHEMBL2295333 0.89 CXCR2 (0.63) CXCR2CCR6
SCHEMBL2291976 0.89 CXCR2 (0.63) CXCR2CCR6
SCHEMBL2291981 0.89 CXCR2 (0.63) CXCR2CCR6
SCHEMBL2297837 0.89 CXCR2 (0.60) CXCR2CCR6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2310359-B1 ORGANIC COMPOUNDS NOVARTIS AG (CH) 2014-01-15 EP disclosed