SCHEMBL15435183

SCHEMBL15435183

CC(C)(C)c1cnc(CN2CCc3cc(S(=O)(=O)Nc4ccc(F)cc4)ccc3C2)nc1

nearest known ligand 0.70

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
MOGAT2 Q3SYC2 20/20 0.70

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16715642 0.92 MOGAT2 (0.77) MOGAT2
SCHEMBL15435300 0.88 MOGAT2 (0.83) MOGAT2
SCHEMBL16715566 0.87 MOGAT2 (0.65) MOGAT2
SCHEMBL15435410 0.87 MOGAT2 (0.68) MOGAT2
SCHEMBL15435366 0.86 MOGAT2 (0.63) MOGAT2
SCHEMBL16715578 0.85 MOGAT2 (0.66) MOGAT2
SCHEMBL16715486 0.84 MOGAT2 (0.67) MOGAT2
SCHEMBL15435275 0.84 MOGAT2 (0.59) MOGAT2
SCHEMBL15435227 0.84 MOGAT2 (0.83) MOGAT2
SCHEMBL16715482 0.84 MOGAT2 (0.77) MOGAT2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2687507-B1 NITROGEN-CONTAINING CONDENSED HETEROCYCLIC COMPOUND TAISHO PHARMACEUTICAL CO LTD (JP) 2016-03-09 EP disclosed
US-9035059-B2 Nitrogen-containing condensed heterocyclic compound TAISHO PHARMACEUTICAL CO., LTD. (JP) 2015-05-19 US disclosed
US-9035059-B2 Nitrogen-containing condensed heterocyclic compound TAISHO PHARMACEUTICAL CO., LTD. (JP) 2015-05-19 US disclosed
EP-2687507-A1 NITROGEN-CONTAINING CONDENSED HETEROCYCLIC COMPOUND Taisho Pharmaceutical Co., Ltd. (JP) 2014-01-22 EP disclosed