Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 9/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.41 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.41 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.41 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.41 |
| ▸ | IL17A | Q16552 | 1/20 | 0.40 |
| ▸ | PARP1 | P09874 | 2/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.34 |
| ▸ | CNR2 | P34972 | 2/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30434565 | 0.87 | BRD4 (0.56) | BRD4HDAC1HDAC3HDAC4HDAC7 | |
| SCHEMBL147598 | 0.87 | BRD4 (0.56) | BRD4HDAC1HDAC3HDAC4HDAC7 | |
| SCHEMBL348683 | 0.79 | BRD4 (0.53) | BRD4HDAC1HDAC3HDAC4HDAC7 | |
| SCHEMBL16625069 | 0.78 | BRD4 (0.41) | BRD4HDAC1HDAC3HDAC4HDAC7 | |
| SCHEMBL30434546 | 0.77 | BRD4 (0.49) | BRD4HDAC1HDAC3HDAC4HDAC7 | |
| SCHEMBL142985 | 0.77 | BRD4 (0.49) | BRD4HDAC1HDAC3HDAC4HDAC7 | |
| SCHEMBL16625066 | 0.77 | TNKS (0.42) | BRD4HDAC1HDAC3HDAC4HDAC7 | |
| SCHEMBL348781 | 0.76 | BRD4 (0.48) | BRD4HDAC1HDAC3HDAC4HDAC7 | |
| SCHEMBL17284266 | 0.75 | BRD4 (0.52) | BRD4HDAC1HDAC3HDAC4HDAC7 | |
| SCHEMBL145706 | 0.74 | BRD4 (0.46) | BRD4HDAC1HDAC3HDAC4HDAC7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2118074-B1 | COMPOUNDS FOR THE PREVENTION AND TREATMENT OF CARDIOVASCULAR DISEASES | RESVERLOGIX CORP (CA) | 2014-01-22 | — | — | EP | disclosed |