SCHEMBL15435945

SCHEMBL15435945

CC(C)(C)OC(=O)N1CCN(CCOCCOCCOCCO)CC1

nearest known ligand 0.44

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 2/20 0.44
USP2 O75604 1/20 0.44
CHRM2 P08172 1/20 0.42
CHRM4 P08173 1/20 0.42
CHRM1 P11229 1/20 0.42
CHRM3 P20309 1/20 0.42
ACKR3 P25106 3/20 0.41
TLR8 Q9NR97 1/20 0.41
HTR1A P08908 1/20 0.41
EPHX2 P34913 4/20 0.41
NR1H2 P55055 1/20 0.39
GPR4 P46093 1/20 0.39
NAMPT P43490 1/20 0.39
DDB1 Q16531 1/20 0.39
CRBN Q96SW2 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25905171 1.00 SMN1; SMN2 (0.44) SMN1; SMN2USP2CHRM2CHRM4CHRM1
SCHEMBL5560225 0.98 SMN1; SMN2 (0.45) SMN1; SMN2USP2CHRM2CHRM4CHRM1
SCHEMBL1730281 0.96 SMN1; SMN2 (0.43) SMN1; SMN2USP2CHRM2CHRM4CHRM1
SCHEMBL6661328 0.88 USP2 (0.44) SMN1; SMN2USP2CHRM2CHRM4CHRM1
SCHEMBL22262696 0.88 USP2 (0.44) SMN1; SMN2USP2CHRM2CHRM4CHRM1
SCHEMBL25678515 0.88 TLR8 (0.46) SMN1; SMN2USP2CHRM2CHRM4CHRM1
SCHEMBL15352136 0.88 USP2 (0.44) SMN1; SMN2USP2CHRM2CHRM4CHRM1
SCHEMBL23251655 0.88 USP2 (0.46) SMN1; SMN2USP2CHRM2CHRM4CHRM1
SCHEMBL20572924 0.87 USP2 (0.43) SMN1; SMN2USP2CHRM2CHRM4CHRM1
SCHEMBL25326510 0.87 USP2 (0.43) SMN1; SMN2USP2CHRM2CHRM4CHRM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4626553-A2 TLR7 AGONISTS AND ANTIBODY-DRUG-CONJUGATES THEREOF Regeneron Pharmaceuticals, Inc. (US) 2025-10-08 EP disclosed
WO-2024118785-A2 TLR7 AGONISTS AND ANTIBODY-DRUG-CONJUGATES THEREOF REGENERON PHARMACEUTICALS, INC. (US) 2024-06-06 WO disclosed
WO-2014016202-A1 METHODS FOR CATALYTIC ALKYLATION OF NUCLEIC ACIDS UNIVERSITÄT BASEL (CH) 2014-01-30 WO disclosed
EP-2689847-A1 Methods for catalytic alkylation of nucleic acids Universität Basel (CH) 2014-01-29 EP disclosed
EP-2689847-A1 Methods for catalytic alkylation of nucleic acids Universität Basel (CH) 2014-01-29 EP disclosed