SCHEMBL15435960

SCHEMBL15435960

Cc1cc(-n2c3ccccc3c3ccccc32)ccc1-c1cc2c3ccccc3n(-c3cccc(-n4c5ccccc5c5ccccc54)c3)c2cc1C

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 5/20 0.44
L3MBTL1 Q9Y468 2/20 0.44
ATM Q13315 1/20 0.44
ALKBH5 Q6P6C2 1/20 0.35
FTO Q9C0B1 1/20 0.35
ALDH1A1 P00352 3/20 0.33
POLB P06746 3/20 0.33
LMNA P02545 1/20 0.33
MAPT P10636 3/20 0.33
MEN1 O00255 3/20 0.33
KMT2A Q03164 3/20 0.33
ALOX15 P16050 2/20 0.33
HSD17B10 Q99714 2/20 0.33
USP2 O75604 1/20 0.33
MYC P01106 1/20 0.33
HSPA1A P0DMV8 1/20 0.33
GAA P10253 1/20 0.33
NR4A1 P22736 1/20 0.33
PTPN7 P35236 1/20 0.33
RECQL P46063 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12938563 0.89 KDM4E (0.39) KDM4EL3MBTL1ATMALKBH5FTO
SCHEMBL10100831 0.88 KDM4E (0.48) KDM4EL3MBTL1ATMALKBH5FTO
SCHEMBL13049632 0.88 KDM4E (0.48) KDM4EL3MBTL1ATMALKBH5FTO
SCHEMBL29462706 0.87 KDM4E (0.52) KDM4EL3MBTL1ATMALKBH5FTO
SCHEMBL63587 0.87 KDM4E (0.52) KDM4EL3MBTL1ATMALKBH5FTO
SCHEMBL29349946 0.87 KDM4E (0.52) KDM4EL3MBTL1ATMALKBH5FTO
SCHEMBL21343713 0.86 KDM4E (0.62) KDM4EL3MBTL1ATMALKBH5FTO
SCHEMBL29727001 0.84 KDM4E (0.46) KDM4EL3MBTL1ATMALKBH5FTO
SCHEMBL22993635 0.84 KDM4E (0.55) KDM4EL3MBTL1ATMALKBH5FTO
SCHEMBL22062923 0.83 KDM4E (0.47) KDM4EL3MBTL1ATMALKBH5FTO

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2688120-B1 LIGHT-EMITTING ELEMENT MATERIAL AND LIGHT-EMITTING ELEMENT TORAY INDUSTRIES (JP) 2017-08-23 EP disclosed
US-9537107-B2 Light emitting device material and light emitting device TORAY INDUSTRIES, INC. (JP) 2017-01-03 US disclosed
EP-2688120-A1 LIGHT-EMITTING ELEMENT MATERIAL AND LIGHT-EMITTING ELEMENT Toray Industries, Inc. (JP) 2014-01-22 EP disclosed