SCHEMBL15439746

SCHEMBL15439746

CN(N=CCCCC=O)[Si](C)(C)C

nearest known ligand 0.40

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
HIF1A Q16665 1/20 0.40
TSHR P16473 2/20 0.34
TRPV1 Q8NER1 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15439744 1.00 HIF1A (0.40) HIF1ATSHRTRPV1
SCHEMBL15439657 0.96 TSHR (0.37) HIF1ATSHRTRPV1
SCHEMBL15439659 0.96 TSHR (0.37) HIF1ATSHRTRPV1
SCHEMBL14799649 0.89
SCHEMBL15440219 0.88
SCHEMBL15440217 0.88
SCHEMBL14799187 0.85
SCHEMBL14799185 0.85
SCHEMBL15440210 0.82 HIF1A (0.42) HIF1ATSHRTRPV1
SCHEMBL15440213 0.82 HIF1A (0.42) HIF1ATSHRTRPV1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9115231-B2 Polymers functionalized with protected hydrazone compounds containing an acyl group BRIDGESTONE CORPORATION (JP) 2015-08-25 US disclosed
US-20140031488-A1 Polymers Functionalized With Protected Hydrazone Compounds Containing An Acyl Group BRIDGESTONE CORPORATION (JP) 2014-01-30 US disclosed