Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCNN1A | P37088 | 17/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | GRM5 | P41594 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.32 |
| ▸ | THPO | P40225 | 1/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL708339 | 0.94 | SCNN1A (0.42) | SCNN1AKMT2AKCNH2KDM4ENPC1 | |
| SCHEMBL15442695 | 0.91 | SCNN1A (0.42) | SCNN1AKMT2AGRM5KDM4EALDH1A1 | |
| SCHEMBL708473 | 0.84 | SCNN1A (0.51) | SCNN1AKDM4ENPC1ALDH1A1CYP1A2 | |
| SCHEMBL15442690 | 0.83 | SCNN1A (0.38) | SCNN1AKDM4ENPC1ALDH1A1CYP1A2 | |
| SCHEMBL708474 | 0.81 | SCNN1A (0.67) | SCNN1A | |
| Hydrochloric Acid SCHEMBL5720664 | 0.80 | SCNN1A (0.41) | SCNN1AKDM4ENPC1ALDH1A1CYP1A2 | |
| SCHEMBL15792081 | 0.80 | SCNN1A (0.38) | SCNN1AKMT2AKDM4ENPC1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL5673038 | 0.79 | SCNN1A (0.50) | SCNN1A | |
| Hydrochloric Acid SCHEMBL4415671 | 0.79 | KDM4E (0.39) | SCNN1AKMT2AKDM4ENPC1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL4878089 | 0.79 | KDM4E (0.39) | SCNN1AKMT2AKDM4ENPC1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140031371-A1 | POLY AROMATIC SODIUM CHANNEL BLOCKERS | PARION SCIENCES, INC. (US) | 2014-01-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140031371-A1 | POLY AROMATIC SODIUM CHANNEL BLOCKERS | HCN4, SCN2B, SCNN1B | SCNN1A 11/4885KMT2A 1510/4885GRM5 1698/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.