SCHEMBL15444681

SCHEMBL15444681

O=C(O)C1C[C@H]1C(=O)O

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8495522 1.00
SCHEMBL65025 1.00 GABRR1 (0.59)
SCHEMBL352933 1.00
SCHEMBL352934 1.00
SCHEMBL373882 1.00
SCHEMBL3404693 1.00 GABRR1 (0.59)
Hydrochloric Acid SCHEMBL28929366 0.96 GABRR1 (0.56)
Hydrochloric Acid SCHEMBL28665294 0.96 GABRR1 (0.56)
Ammonia Solution, Strong SCHEMBL11489327 0.96 GABRR1 (0.56)
Hydrochloric Acid SCHEMBL20556849 0.96 GABRR1 (0.56)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117003776-A Boric acid proteasome inhibitor and application thereof 科辉智药生物科技(深圳)有限公司 2023-11-07 CN disclosed
US-11655260-B2 Heterocyclic compounds as arginase inhibitors GUANGDONG NEWOPP BIOPHARMACEUTICALS CO., LTD. (CN) 2023-05-23 US disclosed
US-20140024650-A1 SULFONAMIDE DERIVATIVE AND USE THEREOF TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2014-01-23 US disclosed