Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 5/20 | 0.35 |
| ▸ | HTR2C | P28335 | 4/20 | 0.34 |
| ▸ | HTR2B | P41595 | 4/20 | 0.34 |
| ▸ | HTR2A | P28223 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | BRD4 | O60885 | 1/20 | 0.34 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.32 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.31 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.31 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.31 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.31 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16803018 | 0.90 | HTR2B (0.36) | GRM2HTR2CHTR2BHTR2AALDH1A1 | |
| SCHEMBL15445749 | 0.90 | HTR2C (0.34) | GRM2HTR2CHTR2BHTR2AALDH1A1 | |
| SCHEMBL15445748 | 0.90 | HTR2C (0.34) | GRM2HTR2CHTR2BHTR2AALDH1A1 | |
| SCHEMBL17549572 | 0.89 | PDE4B (0.37) | GRM2HTR2CHTR2BHTR2APDE4B | |
| SCHEMBL15445747 | 0.88 | GRM2 (0.34) | GRM2HTR2CHTR2BHTR2AALDH1A1 | |
| SCHEMBL15445745 | 0.88 | GRM2 (0.34) | GRM2HTR2CHTR2BHTR2AALDH1A1 | |
| SCHEMBL26277379 | 0.87 | HTR2A (0.39) | HTR2CHTR2BHTR2ABRD4RIPK1 | |
| SCHEMBL18773601 | 0.84 | HPGD (0.37) | HTR2CHTR2BHTR2ARIPK1PDE4B | |
| SCHEMBL10454692 | 0.84 | HPGD (0.37) | HTR2CHTR2BHTR2ARIPK1PDE4B | |
| SCHEMBL16769006 | 0.83 | HTR2A (0.36) | HTR2CHTR2BHTR2ABRD4RIPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140028964-A1 | LIQUID-CRYSTALLINE MEDIUM | MERCK PATENT GMBH (DE) | 2014-01-30 | — | — | US | disclosed |