SCHEMBL15445798

SCHEMBL15445798

CCOc1ccc(OCC2CCC(CC)CC2)c(F)c1F

nearest known ligand 0.41

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
RIPK1 Q13546 1/20 0.41
HTR2A P28223 3/20 0.40
HTR2C P28335 3/20 0.40
HTR2B P41595 2/20 0.40
KDM1A O60341 2/20 0.39
PDE4A P27815 1/20 0.36
PDE4B Q07343 1/20 0.36
PDE4C Q08493 1/20 0.36
PDE4D Q08499 1/20 0.36
GRIN1 Q05586 1/20 0.36
GRIN2B Q13224 1/20 0.36
BRD4 O60885 2/20 0.35
SLC6A9 P48067 1/20 0.35
SSTR5 P35346 1/20 0.35
KCNH2 Q12809 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12366408 0.95 HTR2A (0.38) RIPK1HTR2AHTR2CHTR2BKDM1A
SCHEMBL14391042 0.92 HTR2C (0.40) RIPK1HTR2AHTR2CHTR2BPDE4A
SCHEMBL24170503 0.92 HTR2C (0.40) RIPK1HTR2AHTR2CHTR2BPDE4A
SCHEMBL19169287 0.90 PDE4B (0.41) RIPK1HTR2AHTR2CHTR2BPDE4A
SCHEMBL12740618 0.90 CNR2 (0.38) RIPK1HTR2AHTR2CHTR2BSSTR5
SCHEMBL12735766 0.90 CNR2 (0.38) RIPK1HTR2AHTR2CHTR2BSSTR5
SCHEMBL15445792 0.89 HTR2C (0.38) RIPK1HTR2AHTR2CHTR2BPDE4A
SCHEMBL13929892 0.88 HPGD (0.40) RIPK1HTR2AHTR2CHTR2BKDM1A
SCHEMBL28549719 0.88 HPGD (0.40) RIPK1HTR2AHTR2CHTR2BKDM1A
SCHEMBL13235533 0.87 HTR2C (0.34) RIPK1HTR2AHTR2CHTR2BKDM1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12024665-B2 Polymer-stabilized liquid crystal composition and use thereof BEIJING BAYI SPACE LCD TECHNOLOGY CO., LTD. (CN) 2024-07-02 US disclosed
US-20230265345-A1 LIQUID CRYSTAL COMPOSITION CONTAINING POLYMERIZABLE COMPOUND AND APPLICATION OF LIQUID CRYSTAL COMPOSITION BEIJING BAYI SPACE LCD TECHNOLOGY CO., LTD. (CN) 2023-08-24 US disclosed
US-20230167362-A1 NEGATIVE LIQUID CRYSTAL COMPOSITION, AND LIQUID CRYSTAL DISPLAY ELEMENT OR LIQUID CRYSTAL DISPLAY SHIJIAZHUANG CHENGZHI YONGHUA DISPLAY MAT CO ITD (CN) 2023-06-01 US disclosed
US-11155752-B2 Liquid crystal composition and display device thereof JIANGSU HECHENG DISPLAY TECHNOLOGY CO., LTD. (CN) 2021-10-26 US disclosed
US-20190345386-A1 LIQUID CRYSTAL COMPOSITION AND DISPLAY DEVICE THEREOF JIANGSU HECHENG DISPLAY TECHNOLOGY CO., LTD. (CN) 2019-11-14 US disclosed
EP-2801601-B1 NEMATIC LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE USING SAME DAINIPPON INK & CHEMICALS (JP) 2018-04-25 EP disclosed
US-20170210989-A1 LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY ELEMENT USING THE SAME DIC CORPORATION (JP) 2017-07-27 US disclosed
US-20170210989-A1 LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY ELEMENT USING THE SAME DIC CORPORATION (JP) 2017-07-27 US disclosed
US-20140028964-A1 LIQUID-CRYSTALLINE MEDIUM MERCK PATENT GMBH (DE) 2014-01-30 US disclosed