Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CETP | P11597 | 16/20 | 0.57 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.43 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
| ▸ | PPARA | Q07869 | 1/20 | 0.39 |
| ▸ | KIF11 | P52732 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL759264 | 0.92 | CETP (0.55) | CETPMAPK14 | |
| SCHEMBL760589 | 0.88 | CETP (0.56) | CETPMAPK14 | |
| SCHEMBL758518 | 0.88 | CETP (0.56) | CETPMAPK14 | |
| SCHEMBL760832 | 0.84 | CETP (0.59) | CETPMAPK14 | |
| SCHEMBL759575 | 0.84 | CETP (0.54) | CETPMAPK14 | |
| SCHEMBL760797 | 0.84 | CETP (0.59) | CETPMAPK14 | |
| SCHEMBL15451271 | 0.83 | CETP (0.61) | CETPMAPK14 | |
| SCHEMBL13560451 | 0.83 | CETP (0.57) | CETPMAPK14PPARGPPARAKIF11 | |
| SCHEMBL761626 | 0.83 | CETP (0.55) | CETPMAPK14PPARGPPARA | |
| SCHEMBL3058249 | 0.83 | CETP (0.55) | CETPMAPK14PPARGPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8642576-B2 | Heterocyclic CETP inhibitors | BRISTOL-MYERS SQUIBB COMPANY (US) | 2014-02-04 | — | — | US | claimed |