Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.75 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.75 |
| ▸ | POLB | P06746 | 3/20 | 0.75 |
| ▸ | ALPI | P09923 | 3/20 | 0.75 |
| ▸ | GAA | P10253 | 3/20 | 0.75 |
| ▸ | RECQL | P46063 | 2/20 | 0.75 |
| ▸ | BLM | P54132 | 1/20 | 0.75 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.75 |
| ▸ | ATM | Q13315 | 1/20 | 0.75 |
| ▸ | CYP19A1 | P11511 | 6/20 | 0.60 |
| ▸ | ALPL | P05186 | 2/20 | 0.59 |
| ▸ | ALPG | P10696 | 2/20 | 0.59 |
| ▸ | PKM | P14618 | 2/20 | 0.59 |
| ▸ | MEN1 | O00255 | 1/20 | 0.59 |
| ▸ | MITF | O75030 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.59 |
| ▸ | CYP1A1 | P04798 | 2/20 | 0.53 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26034914 | 0.86 | KDM4E (1.00) | MAPTKDM4EPOLBALPIGAA | |
| SCHEMBL29402477 | 0.86 | KDM4E (1.00) | MAPTKDM4EPOLBALPIGAA | |
| SCHEMBL31436253 | 0.86 | KDM4E (1.00) | MAPTKDM4EPOLBALPIGAA | |
| SCHEMBL1071068 | 0.86 | CYP3A4 (0.65) | MAPTKDM4EPOLBALPIGAA | |
| SCHEMBL130267 | 0.85 | CYP19A1 (0.59) | MAPTKDM4EPOLBALPIGAA | |
| SCHEMBL9205670 | 0.85 | CYP19A1 (0.59) | MAPTKDM4EPOLBALPIGAA | |
| SCHEMBL15453038 | 0.85 | PTPN1 (0.65) | MAPTKDM4EPOLBALPIGAA | |
| SCHEMBL15453094 | 0.85 | CYP19A1 (0.64) | MAPTKDM4EPOLBALPIGAA | |
| SCHEMBL2781916 | 0.83 | MAPT (0.71) | MAPTKDM4EPOLBALPIGAA | |
| SCHEMBL6575796 | 0.82 | CYP19A1 (0.73) | MAPTKDM4EPOLBALPIGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180216152-A1 | METHOD FOR THE BIOTECHNOLOGICAL PRODUCTION OF FLAVONE GLYCOSIDE DIHYDROCHALCONES | SYMRISE AG (DE) | 2018-08-02 | — | — | US | claimed |
| WO-2016050656-A1 | METHOD FOR THE BIOTECHNOLOGICAL PRODUCTION OF FLAVONOIDS | SYMRISE AG (DE) | 2016-04-07 | — | — | WO | claimed |
| EP-3002335-A1 | Process for the biotechnological production of flavonoids | Symrise AG (DE) | 2016-04-06 | — | — | EP | claimed |
| US-20180216152-A1 | METHOD FOR THE BIOTECHNOLOGICAL PRODUCTION OF FLAVONE GLYCOSIDE DIHYDROCHALCONES | SYMRISE AG (DE) | 2018-08-02 | — | — | US | disclosed |
| EP-2692729-B1 | Method for the biotechnological manufacture of dihydrochalcones | SYMRISE AG (DE) | 2016-12-07 | — | — | EP | disclosed |
| US-9359622-B2 | Method for biotechnological production of dihydrochalcones | SYMRISE AG (DE) | 2016-06-07 | — | — | US | disclosed |
| WO-2016050656-A1 | METHOD FOR THE BIOTECHNOLOGICAL PRODUCTION OF FLAVONOIDS | SYMRISE AG (DE) | 2016-04-07 | — | — | WO | disclosed |
| EP-3002335-A1 | Process for the biotechnological production of flavonoids | Symrise AG (DE) | 2016-04-06 | — | — | EP | disclosed |
| US-20140045233-A1 | Method for Biotechnological Production of Dihydrochalcones | SYMRISE AG (DE) | 2014-02-13 | — | — | US | disclosed |
| EP-2692729-A1 | Method for the biotechnological manufacture of dihydrochalcones? | Symrise AG (DE) | 2014-02-05 | — | — | EP | disclosed |