Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 6/20 | 0.37 |
| ▸ | RARB | P10826 | 5/20 | 0.36 |
| ▸ | RARA | P10276 | 2/20 | 0.36 |
| ▸ | RARG | P13631 | 1/20 | 0.36 |
| ▸ | S1PR3 | Q99500 | 4/20 | 0.35 |
| ▸ | PSEN1 | P49768 | 2/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.31 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.31 |
| ▸ | PPARG | P37231 | 2/20 | 0.31 |
| ▸ | PTGES | O14684 | 1/20 | 0.31 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.31 |
| ▸ | FAAH | O00519 | 1/20 | 0.31 |
| ▸ | CETP | P11597 | 1/20 | 0.30 |
| ▸ | PPARA | Q07869 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15460809 | 0.93 | RARB (0.40) | S1PR1RARBRARARARGS1PR3 | |
| SCHEMBL15460654 | 0.90 | CYP17A1 (0.31) | FAAH | |
| SCHEMBL15460780 | 0.88 | S1PR1 (0.34) | S1PR1RARBRARARARGS1PR3 | |
| SCHEMBL15460781 | 0.87 | RARB (0.38) | S1PR1RARBRARARARGS1PR3 | |
| SCHEMBL15460655 | 0.87 | — | — | |
| SCHEMBL15460651 | 0.87 | RARB (0.42) | S1PR1RARBRARARARGS1PR3 | |
| SCHEMBL15460810 | 0.86 | CYP17A1 (0.33) | S1PR1RARBRARAFAAHPPARA | |
| SCHEMBL15461312 | 0.85 | RARB (0.42) | S1PR1RARBRARARARGTHRB | |
| SCHEMBL15460795 | 0.84 | RARB (0.43) | RARBRARARARGTHRBFAAH | |
| SCHEMBL15461325 | 0.84 | RARB (0.40) | S1PR1RARBRARARARGS1PR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9273245-B2 | Compound having 2,2-difluorovinyloxy group or 1,2,2-trifluorovinyloxy group, liquid crystal composition and liquid crystal display device | JNC CORPORATION (JP) | 2016-03-01 | — | — | US | disclosed |
| US-9273245-B2 | Compound having 2,2-difluorovinyloxy group or 1,2,2-trifluorovinyloxy group, liquid crystal composition and liquid crystal display device | JNC CORPORATION (JP) | 2016-03-01 | — | — | US | disclosed |
| US-20140034876-A1 | COMPOUND HAVING 2,2-DIFLUOROVINYLOXY GROUP OR 1,2,2-TRIFLUOROVINYLOXY GROUP, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE | JNC PETROCHEMICAL CORPORATION (JP) | 2014-02-06 | — | — | US | disclosed |
| US-20140034876-A1 | COMPOUND HAVING 2,2-DIFLUOROVINYLOXY GROUP OR 1,2,2-TRIFLUOROVINYLOXY GROUP, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE | JNC PETROCHEMICAL CORPORATION (JP) | 2014-02-06 | — | — | US | disclosed |