Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 known ✓ | P03372 | 1/20 | 0.32 |
| ▸ | FFAR3 | O14843 | 3/20 | 0.44 |
| ▸ | LCK | P06239 | 1/20 | 0.44 |
| ▸ | FYN | P06241 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | CES1 | P23141 | 2/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.33 |
| ▸ | HRH1 | P35367 | 1/20 | 0.33 |
| ▸ | DRD3 | P35462 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL5068220 | 0.97 | FFAR3 (0.47) | FFAR3LCKFYNHDAC1HDAC2 | |
| Acetic Acid SCHEMBL5551624 | 0.86 | CA12 (0.37) | FFAR3LCKFYNHDAC1HDAC2 | |
| Oxalic Acid SCHEMBL7866905 | 0.84 | FFAR3 (0.39) | FFAR3HDAC1HDAC2HDAC3HDAC8 | |
| Oxalic Acid SCHEMBL6313261 | 0.84 | FFAR3 (0.39) | FFAR3HDAC1HDAC2HDAC3HDAC8 | |
| Butane SCHEMBL742874 | 0.79 | — | — | |
| SCHEMBL3669514 | 0.79 | — | — | |
| SCHEMBL57247 | 0.79 | — | — | |
| Bicarbonate SCHEMBL10423661 | 0.79 | FFAR3 (0.35) | FFAR3HDAC1HDAC2HDAC3HDAC8 | |
| Glycolic Acid SCHEMBL5551767 | 0.79 | FFAR3 (0.42) | FFAR3HDAC1HDAC2HDAC3HDAC8 | |
| Acetic Acid SCHEMBL5551190 | 0.79 | FFAR3 (0.41) | FFAR3LCKFYNHDAC1HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 92 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117658714-B | Magnesium-hydrogen composite coating agent, coated seeds and coating method | 上海交通大学 | 2024-06-28 | — | — | CN | claimed |
| CN-114727995-B | Solid oral preparation of eutelone | 北京华昊中天生物医药股份有限公司 | 2024-06-11 | — | — | CN | claimed |
| EP-4062913-B1 | SOLID ORAL FORMULATION OF UTIDELONE | BEIJING BIOSTAR PHARMACEUTICALS CO LTD (CN) | 2024-05-08 | — | — | EP | claimed |
| CN-117752634-A | Rumen slow-release coated ammonium chloride suitable for ruminant animals and preparation method and application thereof | 杭州康德权饲料有限公司 | 2024-03-26 | — | — | CN | claimed |
| CN-117658714-A | Magnesium-hydrogen composite coating agent, coated seeds and coating method | 上海交通大学 | 2024-03-08 | — | — | CN | claimed |
| CN-116687875-A | Ukenafil hydrochloride pharmaceutical composition and preparation method and application thereof | 扬子江药业集团有限公司 | 2023-09-05 | — | — | CN | claimed |
| CN-116509809-A | Compound sodium sulfate tablet and preparation method and application thereof | 山东齐都药业有限公司 | 2023-08-01 | — | — | CN | claimed |
| CN-111972551-B | Rumen bypass preparation and preparation method and device thereof | 浙江新和成股份有限公司 | 2023-07-21 | — | — | CN | claimed |
| CN-116172945-A | Preparation method of acetaminophen oral solution | 华润三九（南昌）药业有限公司 | 2023-05-30 | — | — | CN | claimed |
| CN-112438423-B | Tobacco particles, low-temperature smoke body, preparation method and heating non-combustion appliance | 湖南中烟工业有限责任公司 | 2023-04-11 | — | — | CN | claimed |
| CN-114727995-A | Solid oral preparation of uliteplong | 北京华昊中天生物医药股份有限公司 | 2022-07-08 | — | — | CN | claimed |
| CN-114209084-A | Anti-seepage treatment method for surface of plant particles | 梅尔斯特(广东)生物科技有限公司 | 2022-03-22 | — | — | CN | claimed |
| CN-113397066-A | High-fat feed for deep-sea cultured fish and preparation method thereof | 陵水晨海种业有限公司 | 2021-09-17 | — | — | CN | claimed |
| CN-112535668-A | A preferred method of using levalbuterol sulfate for the treatment of respiratory disorders | 苏州君宁新药开发中心有限公司 | 2021-03-23 | — | — | CN | claimed |
| CN-112438423-A | Tobacco particles, low-temperature smoke body, preparation method and heating non-combustion appliance | 湖南中烟工业有限责任公司 | 2021-03-05 | — | — | CN | claimed |
| CN-112353861-A | Preparation method of pellet particles for conditioning blood stasis constitution | 河南五极中医药研究院 | 2021-02-12 | — | — | CN | claimed |
| CN-108272766-B | Mecobalamin dispersion delayed-release tablet and preparation method thereof | 江苏四环生物制药有限公司 | 2020-07-07 | — | — | CN | claimed |
| CN-108070633-B | Powder-free cold water instant micro-drying culture medium and preparation method thereof | 广东环凯微生物科技有限公司 | 2020-06-16 | — | — | CN | claimed |
| CN-110974807-A | Cetirizine pseudoephedrine sustained-release capsule and preparation method thereof | 白喜平 | 2020-04-10 | — | — | CN | claimed |
| CN-110721171-A | Improved vibration source sheet and preparation method thereof | 安徽九华华源药业有限公司 | 2020-01-24 | — | — | CN | claimed |