Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK1D | P48730 | 5/20 | 0.63 |
| ▸ | CSNK1E | P49674 | 5/20 | 0.63 |
| ▸ | MAPK14 | Q16539 | 14/20 | 0.50 |
| ▸ | MAPK13 | O15264 | 2/20 | 0.38 |
| ▸ | MAPK12 | P53778 | 2/20 | 0.38 |
| ▸ | MAPK11 | Q15759 | 2/20 | 0.38 |
| ▸ | BRD4 | O60885 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1639943 | 0.91 | CSNK1D (0.77) | CSNK1DCSNK1EMAPK14MAPK13MAPK12 | |
| SCHEMBL1640957 | 0.86 | CSNK1D (0.84) | CSNK1DCSNK1EMAPK14MAPK13MAPK12 | |
| SCHEMBL1640975 | 0.86 | CSNK1D (0.69) | CSNK1DCSNK1EMAPK14MAPK13MAPK12 | |
| SCHEMBL1639876 | 0.84 | MAPK14 (0.52) | CSNK1DCSNK1EMAPK14MAPK13MAPK12 | |
| SCHEMBL15203571 | 0.84 | CSNK1D (0.64) | CSNK1DCSNK1EMAPK14MAPK13MAPK12 | |
| SCHEMBL1639785 | 0.79 | CSNK1D (0.60) | CSNK1DCSNK1EMAPK14MAPK13MAPK12 | |
| SCHEMBL1640763 | 0.78 | CSNK1D (0.59) | CSNK1DCSNK1EMAPK14MAPK13MAPK12 | |
| SCHEMBL1640309 | 0.78 | CSNK1D (0.59) | CSNK1DCSNK1EMAPK14MAPK13MAPK12 | |
| SCHEMBL1640953 | 0.78 | CSNK1D (1.00) | CSNK1DCSNK1EMAPK14MAPK13MAPK12 | |
| SCHEMBL1640205 | 0.77 | CSNK1D (0.57) | CSNK1DCSNK1EMAPK14MAPK13MAPK12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2493876-B1 | IMIDAZOLE DERIVATIVES AS CASEIN KINASE INHIBITORS | PFIZER (US) | 2014-02-12 | — | — | EP | disclosed |