Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER4 | P35408 | 15/20 | 0.61 |
| ▸ | PTGER2 | P43116 | 5/20 | 0.61 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3984102 | 1.00 | PTGER4 (0.61) | PTGER4PTGER2MRGPRX4LMNA | |
| SCHEMBL3980141 | 0.93 | PTGER4 (0.58) | PTGER4PTGER2 | |
| SCHEMBL19714256 | 0.92 | PTGER4 (0.73) | PTGER4PTGER2LMNA | |
| SCHEMBL691395 | 0.92 | PTGER4 (0.73) | PTGER4PTGER2LMNA | |
| SCHEMBL3978474 | 0.92 | PTGER4 (0.52) | PTGER4PTGER2LMNA | |
| SCHEMBL3982974 | 0.91 | PTGER4 (0.59) | PTGER4PTGER2LMNA | |
| SCHEMBL3986757 | 0.90 | PTGER4 (0.51) | PTGER4PTGER2LMNA | |
| SCHEMBL3983185 | 0.89 | PTGER4 (0.49) | PTGER4PTGER2 | |
| SCHEMBL3981865 | 0.88 | PTGER4 (0.52) | PTGER4PTGER2 | |
| SCHEMBL3982911 | 0.88 | PTGER4 (0.51) | PTGER4PTGER2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1756042-B1 | SUBSTITUTED METHYL ARYL OR HETEROARYL AMIDE COMPOUNDS | RAQUALIA PHARMA INC (JP) | 2014-02-12 | — | — | EP | disclosed |