Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 19/20 | 0.73 |
| ▸ | TACR2 | P21452 | 11/20 | 0.73 |
| ▸ | TACR3 | P29371 | 12/20 | 0.71 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15397687 | 1.00 | TACR1 (0.73) | TACR1TACR2TACR3 | |
| SCHEMBL15397596 | 1.00 | TACR1 (0.73) | TACR1TACR2TACR3 | |
| SCHEMBL15397688 | 1.00 | TACR1 (0.73) | TACR1TACR2TACR3 | |
| SCHEMBL15397569 | 1.00 | TACR1 (0.73) | TACR1TACR2TACR3 | |
| SCHEMBL15397490 | 0.94 | TACR1 (0.66) | TACR1TACR2TACR3 | |
| SCHEMBL15397597 | 0.93 | TACR1 (0.65) | TACR1TACR2TACR3 | |
| SCHEMBL15397667 | 0.93 | TACR1 (0.65) | TACR1TACR2TACR3 | |
| SCHEMBL1971258 | 0.92 | TACR1 (0.81) | TACR1TACR2TACR3 | |
| SCHEMBL15397548 | 0.91 | TACR1 (0.77) | TACR1TACR2TACR3 | |
| SCHEMBL15397485 | 0.91 | TACR1 (0.77) | TACR1TACR2TACR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2336105-B9 | NITROGEN-CONTAINING HETEROCYCLIC COMPOUND AND USE OF SAME | TAKEDA PHARMACEUTICAL (JP) | 2014-09-17 | — | — | EP | disclosed |
| EP-2336105-B1 | NITROGEN-CONTAINING HETEROCYCLIC COMPOUND AND USE OF SAME | TAKEDA PHARMACEUTICAL (JP) | 2014-02-12 | — | — | EP | disclosed |