Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 7/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 6/20 | 0.47 |
| ▸ | MAPT | P10636 | 5/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 5/20 | 0.47 |
| ▸ | ABCG2 | Q9UNQ0 | 4/20 | 0.47 |
| ▸ | HPGD | P15428 | 4/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 4/20 | 0.47 |
| ▸ | TP53 | P04637 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 4/20 | 0.46 |
| ▸ | NFKB2 | Q00653 | 3/20 | 0.46 |
| ▸ | RELA | Q04206 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.46 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.46 |
| ▸ | CTSL | P07711 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31527884 | 0.92 | MEN1 (0.48) | MEN1KMT2AMAPTMAPK1HPGD | |
| SCHEMBL27183383 | 0.92 | MEN1 (0.48) | MEN1KMT2AMAPTMAPK1HPGD | |
| SCHEMBL31527864 | 0.86 | MAOB (0.45) | MEN1KMT2ACYP3A4MAPTMAPK1 | |
| SCHEMBL27182973 | 0.86 | MAOB (0.45) | MEN1KMT2ACYP3A4MAPTMAPK1 | |
| SCHEMBL2022872 | 0.84 | CYP3A4 (0.47) | MEN1KMT2ACYP3A4MAPTMAPK1 | |
| SCHEMBL2023335 | 0.84 | MEN1 (0.47) | MEN1KMT2ACYP3A4MAPTMAPK1 | |
| SCHEMBL31527893 | 0.81 | CA12 (0.40) | MEN1KMT2AMAPTMAPK1HPGD | |
| SCHEMBL27183279 | 0.81 | CA12 (0.40) | MEN1KMT2AMAPTMAPK1HPGD | |
| SCHEMBL31527674 | 0.79 | AR (0.40) | MEN1KMT2AMAPTMAPK1HPGD | |
| SCHEMBL27182885 | 0.79 | AR (0.40) | MEN1KMT2AMAPTMAPK1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9359622-B2 | Method for biotechnological production of dihydrochalcones | SYMRISE AG (DE) | 2016-06-07 | — | — | US | disclosed |
| US-20140045233-A1 | Method for Biotechnological Production of Dihydrochalcones | SYMRISE AG (DE) | 2014-02-13 | — | — | US | disclosed |