Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 18/20 | 0.54 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20003451 | 0.93 | AR (0.52) | ARNR3C1HDAC1 | |
| SCHEMBL29508773 | 0.93 | AR (0.64) | ARNR3C1HDAC1 | |
| SCHEMBL1715961 | 0.93 | AR (0.64) | ARNR3C1HDAC1 | |
| SCHEMBL1715989 | 0.91 | AR (0.65) | ARNR3C1HDAC1 | |
| SCHEMBL30184886 | 0.91 | AR (0.65) | ARNR3C1HDAC1 | |
| SCHEMBL547082 | 0.83 | AR (0.76) | ARNR3C1HDAC1 | |
| SCHEMBL30184873 | 0.83 | AR (0.76) | ARNR3C1HDAC1 | |
| SCHEMBL19880027 | 0.83 | AR (0.63) | ARNR3C1HDAC1 | |
| SCHEMBL13237811 | 0.81 | AR (0.58) | AR | |
| SCHEMBL2633035 | 0.80 | AR (0.63) | ARNR3C1HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8648105-B2 | Diarylthiohydantoin compounds | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2014-02-11 | — | — | US | disclosed |