Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 4/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | NR3C1 | P04150 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | PTGES | O14684 | 1/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 4/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | MMP2 | P08253 | 1/20 | 0.38 |
| ▸ | MMP9 | P14780 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | PGR | P06401 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9891919 | 0.89 | NPC1 (0.41) | HTTSMN1; SMN2NR3C1FFAR1LMNA | |
| SCHEMBL13605583 | 0.89 | HTT (0.43) | HTTSMN1; SMN2NR3C1TDP1L3MBTL1 | |
| SCHEMBL13605588 | 0.86 | HTT (0.38) | HTTSMN1; SMN2NR3C1FFAR1LMNA | |
| SCHEMBL12087310 | 0.85 | HTT (0.37) | HTTSMN1; SMN2NR3C1L3MBTL1ALDH1A1 | |
| SCHEMBL12938531 | 0.83 | HTT (0.62) | HTTSMN1; SMN2NR3C1TDP1L3MBTL1 | |
| SCHEMBL2623415 | 0.83 | HTT (0.62) | HTTSMN1; SMN2NR3C1TDP1L3MBTL1 | |
| SCHEMBL15315177 | 0.83 | HTT (0.62) | HTTSMN1; SMN2NR3C1TDP1L3MBTL1 | |
| SCHEMBL12900879 | 0.82 | NPC1 (0.39) | HTTSMN1; SMN2NR3C1FFAR1LMNA | |
| SCHEMBL12606789 | 0.82 | GAA (0.53) | HTTSMN1; SMN2TDP1L3MBTL1ALDH1A1 | |
| SCHEMBL12831322 | 0.81 | HTT (0.39) | HTTSMN1; SMN2NR3C1FFAR1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8647164-B2 | Organic electroluminescent element, production method of the same, display device, and lighting device | KONICA MINOLTA HOLDINGS, INC. (JP) | 2014-02-11 | — | — | US | disclosed |