Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 1/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.34 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.34 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.34 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA4 | P22748 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | PER2 | O15055 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15468331 | 0.90 | PIK3CD (0.41) | PIK3CDCHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL8300656 | 0.79 | CHRM2 (0.37) | PIK3CDCHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL8300970 | 0.75 | CHRM2 (0.31) | PIK3CDCHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL13259969 | 0.74 | ACE (0.36) | KMT2A | |
| SCHEMBL22450007 | 0.71 | — | — | |
| SCHEMBL218415 | 0.69 | — | — | |
| SCHEMBL16657578 | 0.69 | — | — | |
| SCHEMBL18656838 | 0.69 | — | — | |
| SCHEMBL10079645 | 0.68 | PIK3CD (0.44) | PIK3CDCHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL23897743 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8648094-B2 | IAP BIR domain binding compounds | PHARMASCIENCE, INC. (CA) | 2014-02-11 | — | — | US | disclosed |