SCHEMBL15468425

SCHEMBL15468425

Nc1nc(I)c2sc(=O)n([C@@H]3O[C@H](CO)C[C@H]3O)c2n1

nearest known ligand 0.49

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
TLR7 Q9NYK1 20/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6970872 0.88 TLR7 (0.50) TLR7
SCHEMBL29450573 0.88 TLR7 (0.50) TLR7
SCHEMBL17822600 0.88 TLR7 (0.50) TLR7
SCHEMBL17822560 0.80 TLR7 (0.47) TLR7
SCHEMBL6972678 0.80 TLR7 (0.74) TLR7
SCHEMBL22281457 0.80 TLR7 (0.74) TLR7
SCHEMBL6985393 0.80 TLR7 (0.74) TLR7
SCHEMBL6973748 0.80 TLR7 (0.47) TLR7
SCHEMBL12956168 0.80 TLR7 (0.74) TLR7
SCHEMBL17904295 0.76 TLR7 (0.52) TLR7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1824482-B1 3, 5-DISUBSTITUTED AND 3,5,7-TRISUBSTITUTED-3H-OXAZOLO AND 3H-THIAZOLO [4,5-d]PYRIMIDIN-2-ONE COMPOUNDS AND PRODRUGS THEREOF ANADYS PHARMACEUTICALS INC (US) 2014-02-12 EP disclosed