Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.34 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.33 |
| ▸ | MPO | P05164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16524069 | 0.89 | HDAC8 (0.37) | HDAC8KEAP1MPO | |
| SCHEMBL9403781 | 0.82 | HDAC8 (0.38) | HDAC8KEAP1MPO | |
| SCHEMBL9403778 | 0.81 | HDAC8 (0.31) | HDAC8KEAP1 | |
| SCHEMBL15469235 | 0.79 | APP (0.41) | — | |
| SCHEMBL17429498 | 0.78 | NR1H2 (0.33) | — | |
| SCHEMBL6434068 | 0.76 | HDAC8 (0.39) | HDAC8KEAP1MPO | |
| SCHEMBL16075810 | 0.75 | NPC1 (0.34) | — | |
| SCHEMBL6322050 | 0.74 | HDAC8 (0.41) | HDAC8KEAP1MPO | |
| SCHEMBL15068354 | 0.74 | HDAC8 (0.41) | HDAC8KEAP1MPO | |
| SCHEMBL11946980 | 0.74 | ESR1 (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140046084-A1 | Siloxane Compound and Cured Product Thereof | CENTRAL GLASS COMPANY, LIMITED (JP) | 2014-02-13 | — | — | US | disclosed |
| US-20140046084-A1 | Siloxane Compound and Cured Product Thereof | CENTRAL GLASS COMPANY, LIMITED (JP) | 2014-02-13 | — | — | US | disclosed |