Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15469586 | 0.87 | ACACB (0.32) | ACACB | |
| SCHEMBL12966785 | 0.87 | ACACB (0.32) | ACACBPARP1 | |
| SCHEMBL15469612 | 0.87 | PARP1 (0.32) | PARP1 | |
| SCHEMBL633818 | 0.85 | PARP1 (0.33) | PARP1 | |
| SCHEMBL634122 | 0.84 | PARP1 (0.31) | PARP1 | |
| SCHEMBL3732925 | 0.83 | PARP1 (0.32) | PARP1 | |
| SCHEMBL15469575 | 0.83 | PARP1 (0.35) | PARP1 | |
| SCHEMBL15469629 | 0.83 | — | — | |
| SCHEMBL15469566 | 0.83 | ADORA2A (0.33) | PARP1 | |
| SCHEMBL15469577 | 0.83 | PARP1 (0.31) | PARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140045890-A1 | NOVEL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2014-02-13 | — | — | US | disclosed |
| US-20140045890-A1 | NOVEL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2014-02-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140045890-A1 | NOVEL COMPOUNDS | CYP1B1, CYP1A1, CYP51A1 | ACACB 2332/4885PARP1 4670/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.