Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 9/20 | 0.45 |
| ▸ | ACACA | Q13085 | 4/20 | 0.45 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | BRD4 | O60885 | 1/20 | 0.36 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | PPARG | P37231 | 1/20 | 0.34 |
| ▸ | PPARD | Q03181 | 1/20 | 0.34 |
| ▸ | PPARA | Q07869 | 1/20 | 0.34 |
| ▸ | LTA4H | P09960 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1547440 | 0.96 | ACACB (0.48) | ACACBACACAFFAR1TDP1BRD4 | |
| SCHEMBL2167110 | 0.87 | ACACB (0.53) | ACACBACACAFFAR1PPARGPPARD | |
| SCHEMBL5942959 | 0.81 | ACACB (0.48) | ACACBACACATDP1 | |
| SCHEMBL5943048 | 0.80 | ACACB (0.46) | ACACBACACATDP1 | |
| SCHEMBL1547268 | 0.79 | ACACB (0.62) | ACACBACACA | |
| SCHEMBL2169083 | 0.74 | ACACB (0.66) | ACACBACACA | |
| SCHEMBL1618710 | 0.73 | KMT2A (0.51) | ACACBACACATDP1 | |
| SCHEMBL19984479 | 0.73 | ACACB (0.55) | ACACBACACAFFAR1PPARGPPARD | |
| SCHEMBL5943027 | 0.72 | ACACB (0.52) | ACACBACACALTA4H | |
| SCHEMBL1547269 | 0.71 | ACACB (0.50) | ACACBACACAFFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2310372-A2 | HETEROCYCLIC COMPOUNDS, PROCESSES FOR THEIR PREPARATION, MEDICAMENTS COMPRISING THESE COMPOUNDS, AND THE USE THEREOF | Sanofi-Aventis (FR) | 2011-04-20 | — | — | EP | disclosed |
| WO-2010003624-A2 | HETEROCYCLIC COMPOUNDS, PROCESSES FOR THEIR PREPARATION, MEDICAMENTS COMPRISING THESE COMPOUNDS, AND THE USE THEREOF | SANOFI-AVENTIS (FR) | 2010-01-14 | — | — | WO | disclosed |