Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRAF | P15056 | 20/20 | 0.78 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10119000 | 0.94 | BRAF (0.78) | BRAF | |
| SCHEMBL10119469 | 0.88 | BRAF (1.00) | BRAF | |
| SCHEMBL10119470 | 0.88 | BRAF (1.00) | BRAF | |
| SCHEMBL10119473 | 0.87 | BRAF (0.76) | BRAF | |
| SCHEMBL18874337 | 0.85 | BRAF (0.89) | BRAF | |
| SCHEMBL10092867 | 0.85 | BRAF (0.74) | BRAF | |
| SCHEMBL10119142 | 0.84 | BRAF (0.92) | BRAF | |
| SCHEMBL10119010 | 0.84 | BRAF (1.00) | BRAF | |
| SCHEMBL10118957 | 0.84 | BRAF (0.90) | BRAF | |
| SCHEMBL10119200 | 0.83 | BRAF (0.79) | BRAF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8653087-B2 | Pyrido [5, 4-D] pyrimidines as cell proliferation inhibitors | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2014-02-18 | — | — | US | disclosed |