Lysophosphatidic Acid

Lysophosphatidic Acid

SCHEMBL1548

CCCCCCCC/C=C\CCCCCCCC(=O)OCC(O)COP(=O)(O)O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
LPAR1 Q92633 10/20 1.00
LPAR4 Q99677 5/20 1.00
LPAR2 Q9HBW0 5/20 1.00
LPAR3 Q9UBY5 5/20 1.00
ENPP2 Q13822 4/20 1.00
LPAR5 Q9H1C0 3/20 1.00
LPAR6 P43657 2/20 1.00
CES2 O00748 1/20 1.00
TRPV1 Q8NER1 1/20 1.00
P2RY10 O00398 6/20 0.72
GPR174 Q9BXC1 6/20 0.72
GPR34 Q9UPC5 3/20 0.72
DGKA P23743 1/20 0.70

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6360211 1.00 LPAR1 (1.00) LPAR1LPAR4LPAR2LPAR3ENPP2
SCHEMBL6360208 1.00 LPAR1 (1.00) LPAR1LPAR4LPAR2LPAR3ENPP2
SCHEMBL6349896 1.00 LPAR1 (1.00) LPAR1LPAR4LPAR2LPAR3ENPP2
Lysophosphatidic Acid SCHEMBL3672549 1.00 LPAR1 (1.00) LPAR1LPAR4LPAR2LPAR3ENPP2
Lysophosphatidic Acid SCHEMBL12388925 1.00 LPAR1 (1.00) LPAR1LPAR4LPAR2LPAR3ENPP2
SCHEMBL6356574 1.00 LPAR1 (1.00) LPAR1LPAR4LPAR2LPAR3ENPP2
SCHEMBL6340952 1.00 LPAR1 (1.00) LPAR1LPAR4LPAR2LPAR3ENPP2
SCHEMBL6349984 1.00 LPAR1 (1.00) LPAR1LPAR4LPAR2LPAR3ENPP2
SCHEMBL6336799 1.00 LPAR1 (1.00) LPAR1LPAR4LPAR2LPAR3ENPP2
SCHEMBL6356572 1.00 LPAR1 (1.00) LPAR1LPAR4LPAR2LPAR3ENPP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 19703 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4746923-A2 DELIVERY SYSTEM COMPRISING LIPID OR POLYMERIC NANOPARTICLES COMPRISING THYROID HORMONES FONDAZIONE RICCARDO TERZI E SILVIO ALBINI (IT) 2026-05-27 EP claimed
EP-3765486-B1 REAGENTS AND METHODS WITH WNT AGONISTS AND BIOACTIVE LIPIDS FOR GENERATING AND EXPANDING CARDIOMYOCYTES UNIV LELAND STANFORD JUNIOR (US) 2026-05-27 EP claimed
CN-122084771-A Detection method of lipidosome in corn embryo and endosperm 2026-05-26 CN claimed
EP-4741813-A1 ANALYSIS METHOD USING LYSOPHOSPHATIDYLCHOLINE COMPOUND CONTAINING STABLE ISOTOPE ELEMENT IN CHOLINE MOIETY SHIMADZU CORPORATION (JP) 2026-05-13 EP claimed
CN-122028939-A Thyroid hormone delivery system comprising lipid or polymer nanoparticles 里卡尔多·泰尔齐与西尔维奥·阿尔比尼基金会 2026-05-12 CN claimed
EP-4724096-A1 GPCR INHIBITORS AND USES THEREOF GPCR Therapeutics, Inc. (KR) 2026-04-15 EP claimed
US-20260092257-A1 METHODS AND COMPOSITIONS FOR GENERATING HEMATOPOIETIC PROGENITOR CELLS TRAILHEAD BIOSYSTEMS INC. 2026-04-02 US claimed
EP-4711446-A1 CELL CULTURE PRODUCT AND USE THEREOF GUANGXIU-GAOXIN LIFE SCIENCES CO., LTD. HUNAN (CN) 2026-03-18 EP claimed
US-12569439-B2 Bottom-up assembly of synthetic extracellular vesicles MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) 2026-03-10 US claimed
CN-121577801-A Group of early warning saliva markers for chronic fluorosis as well as extraction method and application thereof 蚌埠医科大学第一附属医院(蚌埠医科大学附属肿瘤医院) 2026-02-27 CN claimed
EP-0378893-A2 Edible oil/fat compositions Kao Corporation (JP) 1990-07-25 EP claimed
EP-0347526-A1 The fundamental structure of the action of the hormons, the neurotransmetters and the growth factors in the transmission of a signal in the cell and its very important consequences Zagyansky, Y. (FR) 1989-12-27 EP claimed
US-4849019-A MIXTURE OF FATS, OILS, (LYSO)PHOSPHATIDIC ACIDS TO MAKE COOKING PANS NONSTICKING KAO CORPORATION (JP) 1989-07-18 US claimed
EP-0313402-A1 Method for culturing plant tissue MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1989-04-26 EP claimed
EP-0287281-A1 Pan-releasing type oil composition Kao Corporation (JP) 1988-10-19 EP claimed
EP-0088046-B1 LIPIDS IN THE AQUEOUS PHASE CIBA-GEIGY AG (CH) 1987-12-09 EP claimed
EP-0075463-B1 EMULSIFIERS COMPRISING LYSOPHOSPHATIDIC ACID OR A SALT THEREOF AND PROCESSES FOR MAKING A DOUGH FOR USE IN THE PRODUCTION OF FARINACEOUS PRODUCTS KYOWA HAKKO KOGYO KABUSHIKI KAISHA (JP) 1987-05-27 EP claimed
US-4619794-A Spontaneous preparation of small unilamellar liposomes CIBA-GEIGY CORPORATION (US) 1986-10-28 US claimed
US-4478866-A Emulsifiers comprising lysophosphatidic acid or a salt thereof and processes for making a dough containing same KYOWA HAKKO KOGYO KABUSHIKI KAISHA (JP) 1984-10-23 US claimed
EP-0075463-A2 Emulsifiers comprising lysophosphatidic acid or a salt thereof and processes for making a dough for use in the production of farinaceous products KYOWA HAKKO KOGYO KABUSHIKI KAISHA (JP) 1983-03-30 EP claimed