Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 10/20 | 0.71 |
| ▸ | RAB9A | P51151 | 9/20 | 0.71 |
| ▸ | NPC1 | O15118 | 7/20 | 0.71 |
| ▸ | MAPT | P10636 | 7/20 | 0.71 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.71 |
| ▸ | ILK | Q13418 | 5/20 | 0.67 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.65 |
| ▸ | MEN1 | O00255 | 5/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.65 |
| ▸ | GAA | P10253 | 4/20 | 0.65 |
| ▸ | POLB | P06746 | 3/20 | 0.65 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.65 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.65 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.65 |
| ▸ | APP | P05067 | 1/20 | 0.65 |
| ▸ | THRB | P10828 | 1/20 | 0.65 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.65 |
| ▸ | CASP1 | P29466 | 1/20 | 0.65 |
| ▸ | SNCA | P37840 | 1/20 | 0.65 |
| ▸ | CASP7 | P55210 | 1/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30132720 | 0.98 | KDM4E (0.73) | KDM4ERAB9ANPC1MAPTNPSR1 | |
| SCHEMBL196475 | 0.98 | KDM4E (0.73) | KDM4ERAB9ANPC1MAPTNPSR1 | |
| SCHEMBL1549628 | 0.96 | KDM4E (0.71) | KDM4ERAB9ANPC1MAPTNPSR1 | |
| SCHEMBL1550992 | 0.96 | KDM4E (0.71) | KDM4ERAB9ANPC1MAPTNPSR1 | |
| SCHEMBL1550367 | 0.96 | KDM4E (0.71) | KDM4ERAB9ANPC1MAPTNPSR1 | |
| SCHEMBL1550056 | 0.96 | KDM4E (0.71) | KDM4ERAB9ANPC1MAPTNPSR1 | |
| SCHEMBL1549967 | 0.96 | KDM4E (0.76) | KDM4ERAB9ANPC1MAPTNPSR1 | |
| SCHEMBL11910018 | 0.96 | KDM4E (0.71) | KDM4ERAB9ANPC1MAPTNPSR1 | |
| SCHEMBL359505 | 0.96 | KDM4E (0.71) | KDM4ERAB9ANPC1MAPTNPSR1 | |
| SCHEMBL3261894 | 0.96 | KDM4E (0.71) | KDM4ERAB9ANPC1MAPTNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9221770-B2 | Compounds having electron transport properties, their preparation and use | MERCK PATENT GMBH (DE) | 2015-12-29 | — | — | US | disclosed |
| US-20110108819-A1 | COMPOUNDS HAVING ELECTRON TRANSPORT PROPERTIES, THEIR PREPARATION AND USE | MERCK PATENT GMBH (DE) | 2011-05-12 | — | — | US | disclosed |
| EP-2313383-A1 | COMPOUNDS HAVING ELECTRON TRANSPORT PROPERTIES, THEIR PREPARATION AND USE | Merck Patent GmbH (DE) | 2011-04-27 | — | — | EP | disclosed |
| WO-2010020352-A1 | COMPOUNDS HAVING ELECTRON TRANSPORT PROPERTIES, THEIR PREPARATION AND USE | MERCK PATENT GMBH (DE) | 2010-02-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110108819-A1 | COMPOUNDS HAVING ELECTRON TRANSPORT PROPERTIES, THEIR PREPARATION AND USE | SLC25A21, SLCO4C1, SLCO1B3 | KDM4E 4607/4885RAB9A 1290/4885NPC1 53/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.