SCHEMBL15501022

SCHEMBL15501022

CCC(=O)N(C(=O)CC)c1ccc(C2CN(C)Cc3c(Cl)cc(Cl)cc32)cc1

nearest known ligand 0.54

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
SLC9A3 P48764 11/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13449756 0.84 SLC9A3 (0.56) SLC9A3
SCHEMBL4028083 0.83 SLC9A3 (0.53) SLC9A3
SCHEMBL4215501 0.82 SLC9A3 (0.49) SLC9A3
SCHEMBL4027174 0.82 SLC9A3 (0.52) SLC9A3
SCHEMBL4032907 0.81 SLC9A3 (0.52) SLC9A3
SCHEMBL4026492 0.81 SLC9A3 (0.54) SLC9A3
SCHEMBL4028173 0.80 SLC9A3 (0.61) SLC9A3
SCHEMBL4030107 0.80 SLC9A3 (0.53) SLC9A3
SCHEMBL4029827 0.80 SLC9A3 (0.56) SLC9A3
SCHEMBL19593433 0.80 SLC9A3 (0.56) SLC9A3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1838315-B1 SUBSTITUTED 4-PHENYLTETRAHYDROISOQUINOLINES, METHODS FOR PRODUCING THEM, THEIR USE AS DRUG, AND DRUG CONTAINING THEM SANOFI SA (FR) 2014-03-12 EP disclosed